Ovarian Cancer

Scientists trigger suicide switch in cancer cells

Published in Gene Therapy Weekly, July 15th, 2004

Genetically engineering viruses to carry a suicide gene into ovarian cancer cells could become a potent way to tackle the disease, a Cancer Research UK scientist revealed at a conference in Glasgow, Scotland, on June 22, 2004.

All normal cells have the gene, called Smac, switched on to trigger their own death when they reach a certain age. But cancer cells carry a faulty version of the gene and carry on dividing and growing well beyond their allotted lifespan.

Iain McNeish, presented his work on the Smac gene at the Cancer Research UK Beatson International Cancer Conference. He believes designing therapies to mimic or restore the function of Smac...

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Source: Gene Therapy Weekly (2004-07-15)

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