Colon Cancer
DNA lesion type defines death characteristics of colon carcinoma cells
Published in Gene Therapy Weekly, July 22nd, 2004
"The pleiotrophic cellular response to DNA damage includes activation of cell cycle checkpoints, induction of DNA repair pathways, and initiation of programmed cell death, among others. The fate of cells with damaged DNA depends on the coordination of these different responses. The clinical efficacy of genotoxic therapies is influenced by cell fate and thus by how the DNA damage response is coordinated," scientists in the United States report.
"While a great deal has been learned about how different DNA lesions activate distinct cell cycle checkpoints and DNA repair pathways,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2004-07-22)
More Articles from Gene Therapy Weekly
- Drug Development
Novel lipid-based cochleates drive gene uptake into mammalian cells - Gene Expression Systems
External heat treatment controls gene activation in muscle cells - Metastasis
Flt-1 gene transfer suppresses gastric cancer peritoneal metastasis - Nephropathy
Decoy nucleotides mitigate the formation of diabetic kidney disease - Stem-Cell Research
Genetically modified stem cells reverse neurodegenerative symptoms in mice - Bacterial Infection
C. pneumoniae-induced IFN-gamma dependent on 88-IFN-alpha beta-STAT1 signaling - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
