Published in Gene Therapy Weekly, July 29th, 2004
"Neuropilin-1 (NRP-1), a recently identified coreceptor for vascular endothelial growth factor (VEGF), is expressed by several non-gastrointestinal tumor types and enhances prostate cancer angiogenesis and growth in preclinical models. We investigated the expression and regulation of NRP-1 and the effect of NRP-1 overexpression on angiogenesis and growth of human colon adenocarcinoma by immunohistochemistry and in situ hybridization," scientists writing in the American Journal of Pathology report.
"NRP-1 was expressed in 20 of 20 human colon adenocarcinoma specimens but...
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