Gastroenterology
Recombinant adenoviral vector encodes functional vasoactive intestinal peptide
Published in Gene Therapy Weekly, August 26th, 2004
"Vasoactive intestinal peptide (VIP) is a small neuropeptide, which exerts pleiotropic functions. Based on its immunomodulatory, secretory, and possibly trophic effects, VIP is a valuable candidate molecule for the management of autoimmune disease. The purpose of this study was to develop a recombinant viral vector capable of directing the expression of functional VIP," investigators in the United States report.
"The vector rAd5CMVhVIP was constructed and used to infect 293 cells. VIP expression was measured by an enzyme-linked immunosorbent assay (ELISA) and function was...
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Source: Gene Therapy Weekly (2004-08-26)
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