Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . September 2nd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Brain Cancer - Midkine promoter-based gene therapy decimates malignant glioma
Breast Cancer - Bcl-2 antisense oligodeoxynucleotide chemosensitizes breast carcinoma cells
Drug Resistance - Down-regulated survivin sensitizes human melanoma cells to topotecan
Phytotherapy - Phytoestrogens regulate genes in breast cancers that lack estrogen receptors
Tissue Engineering - Tissue scaffolds ease drug and gene delivery to healing wounds
Angiology - Intracoronary transfer of adenylyl cyclase increases left ventricle function
Antisense Technology - Antisense RNA staunches glioma angiogenesis and growth
Behavior - Brain's reward circuitry revealed in procrastinating primates
Bioengineering - Ion-sensitive nanoparticles escort gene therapy
Bone Repair - Stem cell gene therapy produces regenerative bone protein in healing mice
Business & Finance - Life sciences company reports on second quarter 2004 results
Cancer Immunotherapy - Lentiviral transfection of dendritic cells upregulates alloreactive T cells
Cancer Therapy - Biotechnology company and ViroTarg sign anticancer license agreement
Carcinogenesis - Sulforaphane modulates genes linked to cancer formation
Cervical Cancer - Mechanism described by which POU transcription factor represses growth in vitro
Chronic Myelogenous Leukemia - Child with atypical CML treated successfully with imatinib mesylate
Collaborations - University signs deal for cancer gene therapy
Colon Cancer - CRE-decoy oligonucleotides and chemotherapy reduce colorectal cancer growth
Colon Cancer - Triplex-forming oligonucleotides halt colon carcinoma growth in mice
Dermatology - Gene gun-based transfection examines the underpinnings of melanogenesis
Drug Delivery - Photocrosslinked surface eroding polyanhydrides offer long-term DNA release
Drug Delivery - Positive results reported: Electroporation-enabled DNA delivery sans anesthesia
Drug Delivery - Recombinant polyomavirus-like particles extend small molecule delivery
Endocrinology - Androgen-induced stimulation of prostate cancer requires estrogen receptor beta
Endocrinology - Leptin-receptor genes stimulate the hypothalamo-pituitary-gonadal axis
Expression Vectors - A new host/plasmid system eliminates antibiotics during vector cultivation
Gastric Cancer - B7-1 gene transduction enhances immune response to metastatic tumor cells
Gastric Cancer - The novel cDNA DEGA may play a role in the etiology of gastric adenocarcinoma
Gene Expression - HDAC inhibitors trigger apoptosis in HPV+ cells by inducing E2F-p73 pathway
Gene Silencing - Antisense trefoil factor family transcripts reside in murine kidneys and livers
Gene Therapy - Mobilization of antiretroviral SIV gene therapy vector is feasible
Gene Transfer - Adenoviral vector containing tumor-specific constructs target ovarian cancer
Gene Transfer - Physiological conditions highlight the efforts of non-viral gene vectors
Gene Transfer - Receptor-specific polyplexes pinpoint breast cancer cells
Gene Transfer - Solid lipid nanoparticles are well-suited for non-viral transfection
Genetic Risk - Polymorphism-197C/G in XBP1 may indicate a genetic risk for schizophrenia
Genomics - Abrin-a A chain from a synthesized gene is catalytically and functionally active
Genomics - PRDM5 gene is silenced in human cancers and has growth-suppressive activities
HIV/AIDS Gene Therapy - Lentivirus-based antisense vector inhibits HIV replication
Hematology - Erythropoietin is a potent booster of metallothionein gene expression
Hematology - Fanconi anemia C gene product regulates differentiation and inflammation genes
Immunodeficiency - Novel strategy fixes mutation without raising lymphoma risks
Immunology - Stress activation boosts the immunogenicity of tumor cells
Leukemia - Cell loading system used in phase I/II gene therapy trial for leukemia
Metabolic Disease - Gene transfer causes behavioral recovery in murine phenylketonuria models
Molecular Virology - MOI determines proviral copy number in lentivirus-transduced repopulating cells
Neurobiology - A novel retina culture technique highlights the value of new therapeutics
Neurodegeneration - Interleukin-4 inaugurates HSV-based gene therapy in multiple sclerosis models
Oncology - Tumor cells that secrete interleukin-13 have diminished tumorigenicity
Personnel - RNAi company names Benjamin S. Levin general counsel
Pharmaceutical & Drug Development - DNA minor groove binders potential antitumor and antimicrobial agents
Pharmacology - Maspin gene expression could be exploited as anti-cancer therapy
Product Licensing - Hybridon licenses key VEGF patents for treatment of ocular diseases
Recombinant Research - A method is developed for rapid analysis of recombinant proteins
Rheumatology - Cathepsin L-targeted ribozymes limit the devastation of rheumatoid arthritis
Stem Cell Research - Britain issues its first cloning license for stem cell research
Thrombophilia - Fetal thrombophilia alone not associated with fetal vascular lesions of placenta
Transfection - Herpes simplex virus type 1 can infect cells via non-HSV-specific receptors
Transgene Expression - The tet-off system offers tight regulation of adeno-associated virus vectors
Vector Development - Antisense oligonucleotides require effective delivery for optimal effects
Vector Development - Recombinant Escherichia coli delivers genes to airway epithelial cells
Vector Development - Recombinant bispecific antibodies guide adenoviruses to select tumor cells
Vectors - Retroviral gene therapy? ASLV, HIV, MLV show distinct target site preferences
Viral Vector - Herpes simplex virus vectors create transgene persistence in motor neurons
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