Susan Hasty, Publisher
Table of Contents . . . September 9th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Fetal Medicine - In utero gene delivery may be capable of treating muscular dystrophy
Oncovirus - Recombinant Sendai virus selects for and lyses human tumor cells
Pulmonary Medicine - Secretory leukoprotease inhibitor can be targeted for treating lung cancer
Type 1 Diabetes - Vascular endothelial growth factor gene delivery promotes islet vessel growth
Urology - Histone deacetylase inhibitors improve the transfection of bladder cancer cells
Addiction Medicine - Researchers find new hope for detecting gene doping
Anticancer Therapy - Gene-deleted oncolytic adenovirus vector activates cancer therapy
Bioengineering - Delta LNGFR is a viable gene marker in engineered tissues
Bioinformatics - The new siRNA Selection Server automates short oligonucleotide design
Biotechnology - Optical biosensor addresses a whole bioprocess in real time
Breast Cancer - EGR3 involved in estrogen-signaling pathway in breast cancer
Breast Cancer - gamma Synuclein stimulates hormone-responsive mammary tumorigenesis
Cancer Therapy - BNO69 angiogenesis gene discovery published in journal
Cervical Cancer - New DNA vaccine targets proteins expressed in cervical cancer cells
Collaborations - Neugene antisense deal inked with USAMRIID on biodefense agents
Colon Cancer - Hyaluronan pairs with CD44 to encourage colon carcinoma cell invasion
Cytomegalovirus - Gene transfer used to activate CMV specific T cells
Diabetic Nephropathy - Transforming growth factor blockade treats diabetes-related kidney disease
Drug Delivery - Electroendocytosis guides therapeutic molecules into cells
Drug Resistance - Oblimersen antagonizes Bcl-2 to treat small cell lung cancer
Drug Resistance - Small interfering RNAs that target the MDR1 gene reverse multidrug resistance
Endocrinology - Adiponectin may treat vascular disorders related to obesity
Epstein-Barr Virus - EBNA-2 gene variant may play role in pathogenesis of oral hairy leukoplakia
Finance - Cancer company reports Q2 revenues of $212,000, down from same time last year
Finance - Genomic-analysis technology company reports improved financial results
Finance - Telomerase technology company reports Q2 loss of $8.9 million
Gene Regulation - BCNU promotes the death of oligodendroglioma-derived cells
Genetics - Exploiting gene mutations may combat osteoporosis and obesity
Genomics - CodY is activated by direct interaction with branched-chain amino acids
Genomics - Effective liver cell transduction relies on viral second-strand DNA synthesis
Genomics - Nucleophosmin partners with nuclear factor-kappa B to activate the SOD2 gene
Immunology - Cells engineered to secrete soluble CD70 boost antitumor immunity
Immunology - Interferon receptor regulation enhances the efficacy of cancer therapy
Leiomyoma - Early growth response-1 may have gene therapy potential for uterine fibroids
Macular Degeneration - Ophthalmology company files IND for therapeutic RNAi
Muscular Dystrophy - Forced dystrophin expression improves calcium handling in muscle cells
Neuroscience - Enzyme restoration prevents neuropathology in murine models of Hurler syndrome
Neuroscience - Oligonucleotide decoys modulate trauma response in the nervous system
Oncogenesis - DLEU2 is an antisense regulator of human and murine RFP2/LEU5 genes
Orthopedics - Orthopedic products company names new member to board of directors
Pancreatic Cancer - Triplex-forming oligonucleotide curtails the oncogene Ki-ras
Parkinson Disease - FDA clears gene therapy trial for Parkinson disease
Personnel - Bioscience company appoints Dale Ando VP of therapeutic development, CMO
Personnel - Cell-therapy company announces executive appointments
Personnel - Riaz Bandali joins board of electroporation company
Poxvirus Vaccine - Understanding of poxvirus pathogenesis advanced by deleting viral genes
Recombinant Research - A novel recovery approach for separation and concentration is described
Renal Cell Carcinoma - Bcl-2 antisense nucleotide sensitizes interferon-resistant renal cancer to Fas
Rheumatology - Early experimental osteoarthritis surrenders to gene therapy
Transfection - Virus-specific properties encourage brain cell gene transfer
Ulcerative Colitis - Enrollment continues in retreatment phase of Nuvion trial
Vaccine Delivery - Drug delivery systems reviewed
Vector Development - Photochemical transfection enhances the cytotoxicity of suicide gene therapy
Vectors - X marks the spot: Vector insertion is viral-specific
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