Susan Hasty, Publisher
Table of Contents . . . September 16th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cardiomyopathy - Partial-heart dystrophin gene transfer may correct hereditary heart disease
Immunology - Retinal transduction does not generate immune tolerance to transgene products
Neuroscience - Dual-cell, dual-gene therapy provides neuroprotection against excitotoxicity
Oncology - Virus-mediated p14(ARF) expression prompts apoptosis in osteosarcoma cells
Pulmonary Medicine - Adenovirus vectors trigger survival signals in the lungs
AIDS/HIV Vaccine - Camelized VH intrabodies against vif neutralize HIV-1 infectivity
Asthma - Company reaches clinical milestone related to IL-9 antibody alliance
Bacterial Infection - Biopharmaceutical company announce milestones in StaphVAX development
Bioregulation - Engineered riboregulators may be able to control gene expression
Business Update - Genetics company changes corporate identity to Icoria, Inc.
Cancer Immunotherapy - T cells with dual receptors suppress cancer growth
Cancer Therapy - Biopharmaceutical company announces positive results in cancer management trial
Cancer Therapy - Neovastat activates signals that destroy fibrin provisional matrices
Cardiology - Study links physiologic phenotype with defined genotype
Collaborations - Biotechcompany and Novosom enter collaboration and commercial option agreement
Collaborations - Icon Genetics and Berlex enter strategic alliance
Drug Delivery - External packing of DOTAP/DOPE and DC-Chol/DOPE lipoplexes is advantageous
Drug Delivery - Study supports electroporation-mediated DNA delivery without anesthesia
Drug Development - Chromatin insulators may increase the efficacy of gene therapy
Drug Development - Iowa researchers collaborate on RNAi technology for neurodegenerative disease
Drug Discovery - Company announces patent issuance for E2F transcription factor decoy technology
Drug Resistance - Suppressed Ras increases the sensitivity of glioma to cisplatin in vitro
Finance - Drug development company reports 2Q loss of less than $0.01 per share
Finance - Drug-discovery company announces second-quarter 2004 financial results
Finance - Electroporation-focused company report Q2 net loss of $2.2 million
Finance - Gene therapy company announces second-quarter loss of $2.3 million
Finance - RNAi company updates Q2, reports $0.2 million in revenues
Gene Delivery - Cholesterol ratio affects the interlamellar spacing of lipoplexes
Gene Regulation - Transcription factor CP2 helps activate mBMP4 in mesenchymal stem cells
Gene Silencing - Polycomb target gene silencing associates with histone H3 Lys 27 methylation
Gene Therapy - Data describe selectivity, efficacy, lack of toxicity of oncolytic adenovirus
Gene Transfer - Culture systems improve the study of gene function in inaccessible tissue
Gene Transfer - Pyridinium cationic lipids surpass the efforts of classic DTOAP-based formulas
Gene Transfer - Temperature and pH responsive polymers react to environmental changes
Heart Attack - Alliance to bring stem cell recruiting myoblast technology to clinic
Hematopoiesis - Definitive hematopoiesis requires mixed-lineage leukemia gene
Hepatology - Superoxide dismutase gene delivery protects murine livers from acute injury
Immunology - Bruton's tyrosine kinase gene knockout mice exhibit genomic alterations
Information Technology - Strategic alliance formed to develop gene expression simulation technnology
Medical Devices - Life science companies collaborate to develop automated solutions
Oncology - Pigment epithelium-derived factor gene therapy may treat liver cancer
Ophthalmology - Non-viral vectors deliver plasmid DNA to rabbit eye tissues
Pain Relief - Proangiogenic growth factor upregulates myoglobin to relieve ischemic muscles
Renal Cell Carcinoma - FDA grants fast-track status to temsirolimus
Stem Cell Research - Gene expression changes in course of neural progenitor cell differentiation
Therapeutic Proteins - Chromos enters into agreement with Centocor for development of cell lines
Vector Development - Novel biodegradable multi-block copolymers may be suitable for gene delivery
Virology - Virus known for its photo ops makes its movie screen debut
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