Stem Cell Research
Known and novel transcripts overexpressed in hematopoietic stem cells identified
Published in Gene Therapy Weekly, September 23rd, 2004
According to recent research published in the journal Cancer Research, "The human CD34+/CD38-/Lin- cell subset, comprising approximately 1-10% of the CD34+ cell population, contains few of the less primitive hematopoietic (lineage-committed) progenitor cells (HPCs) but most of the primitive in vivo engrafting (lympho-)hematopoietic stem cells (HSCs).
"We analyzed gene expression in CD34+/CD38-/Lin- cell populations isolated from normal human adult donor bone marrow, neonatal placental/umbilical cord blood, and mobilized adult donor peripheral blood...
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Source: Gene Therapy Weekly (2004-09-23)
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