Published in Gene Therapy Weekly, September 23rd, 2004
According to recent research published in the journal Cancer Research, "The human CD34+/CD38-/Lin- cell subset, comprising approximately 1-10% of the CD34+ cell population, contains few of the less primitive hematopoietic (lineage-committed) progenitor cells (HPCs) but most of the primitive in vivo engrafting (lympho-)hematopoietic stem cells (HSCs).
"We analyzed gene expression in CD34+/CD38-/Lin- cell populations isolated from normal human adult donor bone marrow, neonatal placental/umbilical cord blood, and mobilized adult donor peripheral blood...
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