Susan Hasty, Publisher
Table of Contents . . . September 30th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Brain Cancer - iBAC system-mediated gene delivery stifles glioma cell growth
Coronary Artery Disease - Myocardial gene therapy initiates collateral development in occluded hearts
Head and Neck Cancer - Mutant p27 gene elicits anticancer effects in oral cancer cell lines
Immunology - Nucleosome-specific genetically engineered T cells staunch autoimmune disease
Metabolic Disease - Virus vector-mediated gene transfer corrects phenylketonuria in murine models
Alzheimer Disease - 12-Lipoxygenase blockade protects neurons from peptide-induced degeneration
Angiology - Superoxide dismutase gene transfer improves impaired aortic relaxation
Angioplasty - Inhibition may aid protective effect of IL-10 on postangioplasty restenosis
Anthrax - Researchers improve detection of diverse anthrax strains
Antisense Technology - Double-stranded complexes increase antisense oligonucleotide uptake
Autoimmune Disease - Genetically modified bone marrow cells produce tolerance to self antigens
Bladder Cancer - Novel gene therapy for bladder cancer shows strong results in animal studies
Cancer Therapy - Preclinical data demonstrate antitumor effects of T-oligo technology
Cardiology - Vasorin mediates the arterial response to injury
Collaborations - Pharmaceutical firm collaborates for depression gene program
Congenital Muscular Dystrophy - Laminin alpha1 chain transgenes correct genetically deficient mice
Drug Delivery - Collagen and methylated collagen gene carriers offer sustained transgenics
Drug Resistance - Cells with pleiotropic drug resistance can be targeted with anticancer therapy
Endocrinology - Gene expression profiling classifies parathyroid growths
Epilepsy - Pharma company receives tentative approval for Gabapentin capsules
Finance - Biopharmaceutical company reports limited strong revenue growth for FY 2004
Finance - Protien therapeutics company announces strong first half 2004 results
Gene Delivery - Outgrowth endothelial cells host gene vectors that target tumor vessels
Gene Expression - Molecular images track the activity of cancer gene therapy
Gene Suppression - Several strategies eliminate multidrug resistance gene expression
Gene Therapy - Modular protein engineering safer than viral vectors for gene therapy
Gene Therapy - RNA interference is a potent tool for gene-specific therapeutics
Gene Transfer - Centrifugation concentrates retroviruses used for transfection
Gene Transfer - Inflammation constrains a key gene therapy receptor on endothelial cells
Gene Transfer - Nuclear images monitor the efforts of PEGylated polyethylenimine vectors
Genomics - Phenotype suggests a prime function for Sox11 in tissue remodeling
Geriatrics - Improved vector systems will help patients with neurological disorders
HIV/AIDS - HIV vaccine progresses towards next phase
HIV/AIDS Research - SIV vaccine study data presented at AIDS Vaccine 2004
Human Growth Hormone - FDA defers decision on Omnitrope application
Immunology - Sphingosine kinase 1 knockdown vanquishes proinflammatory mediators
Information Technology - Bioinformatic company announces marketing alliance with Science-Partners
Medical Device - New miniaturized cardiovascular ultrasound announced
Muscular Dystrophy - Biopharmaceutical company awarded grant from muscular dystrophy association
Mutagenesis - Screenings for redundancies could cure many genetically-related disorders
Neurodegeneration - Neural stem cells have the potential for reconstructing damaged nervous systems
Neuroscience - Glial cell line-derived neurotrophic factor lowers tyrosine hydroxylase levels
Oncology - RNA molecules have shown promise as cancer therapy
Parkinson Disease - FDA approves Parcopa orally dissolving tablets for Parkinson disease
Parkinson Disease - Proteins delivered via engineered virus prevented loss of nerve cells
Peripheral Artery Disease - Clinical trial begins for therapy designed to grow new blood vessels
Reproductive Medicine - siRNA Expression vector useful for gene silencing in preimplantation embryo
Stem Cell Research - Genetically altered embryonic stem cells acquire dopaminergic neuronal traits
Stem Cell Research - Novel system characterizes the expression of totipotency-specific genes
Vascular Gene Therapy - NIH awards grant to conduct research for vascular gene delivery
Vector Development - Cyclodextrin-modified polyethylenimine polymers deliver genes without toxicity
Vector Development - Lipoplexes bearing triantennary galactosyl ligand strengthen gene transfer
Vectors - FIV-based lentiviral vector used for gene delivery to treat metabolic diseases
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