Cancer Therapy

Gene therapy for bladder cancer shows strong results in animal studies

Published in Gene Therapy Weekly, October 7th, 2004

Gene therapy that causes the bladder to act like a "bioreactor" to produce and secrete the anticancer agent interferon-alpha has shown dramatic benefits in preclinical tests, say researchers at The University of Texas M.D. Anderson Cancer Center.

The researchers say their findings, published in Molecular Therapy, suggest this gene therapy strategy holds much promise for treating aggressive human superficial bladder cancer and that a clinical trial is being planned.

Human bladder tumors growing in experimental mice substantially decreased in size after two treatments with novel gene-based therapy. There was little or no evidence of cancer cells...

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Source: Gene Therapy Weekly (2004-10-07)

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