Radiotherapy
Heat shock protein 27 protects human cells against ultraviolet C-mediated death
Published in Gene Therapy Weekly, October 7th, 2004
"It is an intriguing problem whether heat shock proteins (HSPs) play a protective role in ultraviolet C (UVC)-induced cell death in human cells, and the problem has not been solved. To search for the HSPs involved in UVC resistance, gene expression profiles using cDNA array were compared between UVC-sensitive human RSa cells and their UVC-resistant variant AP(r)-1 cells. The expression levels of heat shock protein 27 (HSP27) were lower in RSa cells than in AP(r)-1 cells," scientists in Japan report.
"RSa cells transfected with sense HSP27 cDNA showed slightly lower...
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Source: Gene Therapy Weekly (2004-10-07)
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