Cancer Therapy
Short interfering RNA targeting survivin generates apoptosis in cancer cells
Published in Gene Therapy Weekly, October 14th, 2004
According to recent research from Japan, "gene targeting using short interfering RNA (siRNA) has become a common strategy to explore gene function because of its prominent efficacy and specificity. For the application of siRNA technology to gene therapy, however, still more efficient transduction of siRNA into target cells is needed. In this study, we developed an adenoviral vector harboring a tandem-type siRNA expression unit, in which sense and antisense strands composing the siRNA duplex were separately transcribed by two human U6 promoters."
"Targeting survivin, an...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2004-10-14)
More Articles from Gene Therapy Weekly
- Genetic Disorders
Supplementation therapy bypasses defective genes by boosting alternate ones - Head and Neck Cancer
Topoisomerase inhibitors augment the effect of cancer gene therapy - Vascular Occlusion
Monocyte chemoattractant protein-1 gene inhibition thwarts in-stent restenosis - Vector Development
Polymer-coated adenoviral vectors offer bioavailability with less toxicity - Alzheimer Disease
Genomics company awarded grant to conduct Alzheimer genome study - Alzheimer Disease
Phase I trial of CERE-110 for patients with AD begins - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
