Recombinant Therapy
Artificial trimeric TRAIL has the potential to treat cancer
Published in Gene Therapy Weekly, October 28th, 2004
According to a study from the United States, "tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a type II transmembrane cytokine molecule of the TNF family. Soluble recombinant TRAIL has been shown to induce apoptosis in a wide variety of cancer cells in vitro and to specifically limit tumor growth without damaging normal cells and tissues in vivo. These results suggest a strong potential of TRAIL as an anticancer therapy."
"Here we report an artificial TRAIL gene that expresses and secretes trimeric TRAIL into the culture supernatant. This novel TRAIL gene is...
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Source: Gene Therapy Weekly (2004-10-28)
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