Neuroscience
Novel transfection method devised for mature hippocampal neurons
Published in Gene Therapy Weekly, October 28th, 2004
"Numerous methods exist for transfecting postmitotic neurons, for example, DNA/calcium phosphate coprecipitation, cationic lipids, viruses, and physical methods such as microinjection, electroporation, and biolistics," scientists in Germany explained. "Most methods, however, are either toxic to the cell, yield only poor transfection efficiencies, or cells have to be electroporated before plating."
In the Journal of Neurobiology, B. Goetze and coauthors at the Max Planck Institute for Developmental Biology presented "a standardized and fast...
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Source: Gene Therapy Weekly (2004-10-28)
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