Susan Hasty, Publisher
Table of Contents . . . November 4th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Bioreactors - Polycation-mediated precipitation captures plasmid DNA from alkaline lysate
Breast Cancer - The adenoviral type 5 E1A gene sensitizes breast tumors to paclitaxel
Pancreatic Cancer - Suppressed synthesis of HMGA1 protein treats pancreatic carcinomas in mice
Tumor Suppression - Low-voltage electroporation augments antiangiogenic cancer gene therapy
Vector Development - Herpesvirus-based vector guides fusion protein to cancer cells
Acute Myeloid Leukemia - Loss of clone with FLT3 gene mutation at relapse does not improve AML prognosis
Alzheimer Disease - Biotechcompany scientist presented with award from Alzheimer Association
Antibiotic Resistance - Biotech company working to address problem of antibiotic resistance
Antisense Technology - Antisense inhibitors of TRADD could modulate TNF-related pathologies
Antisense Technology - The antisense mRNA sONE offers endothelial-cell specific gene expression
Awards - Biotech firm lauds Nobel winner, announces olfactory-based government contract
Awards - Genetics products company named to Technology Fast 50 Program for Washington
Basal Cell Carcinoma - Gli proteins up-regulate expression of basonuclin in basal cell carcinoma
Breast Cancer - Well-differentiated breast tumors have more 16q loss than poorly differentiated
Cancer Research - Biopharma company announces update on trial of compound for advanced cancers
Cancer Research - Leukemia society awards two $5 million grants to develop anticancer therapies
Cancer Research - New therapy may counteract Paclitaxel resistance in cancer cells
Cancer Therapies - Pharma company presented six studies at cancer therapy conference
Cardiology - Electroporation of hepatocyte growth factor DNA treats cardiomyopathy
Cardiovascular Disease - Biosciences company enters collaboration to study genetics of heart disease
Collaborations - Biogen enters pharmacodiagnostic research collaboration
DNA Damage - p53-dependent transcription exhibits on and off responses after genotoxic stress
Dermatology - Biopharmaceutical company announces resutls of dermatological disorder trial
Drug Delivery - Low molecular weight chitosan fractions exhibit marked solubility
Drug Development - Biotechnology company files a request of re-examination of Benitec
Drug Development - Sense oligonucleotides targeting VEGF may help patients with ischemic tissues
Enzymology - Superoxide dismutase gene transfer may treat complex I deficiency disorders
Finance - Biotherapeutics announces third-quarter 2004 results
Finance - Company raises $12 million to fund gene therapy
Gastric Cancer - Expression of 7 ARP2/3 complex genes are decreased in gastric cancer
Gastric Cancer - KiSS-1 downregulation causes tumor invasion/worse prognosis in gastric cancer
Gene Expression - Genomics company announces gene study in human embryonic stem cells
Gene Profiling - Biological materials provider signs distribution agreement with GE Healthcare
Gene Promotion - Chimeric constructs target heterologous genes in cancer-derived cells
Gene Therapy - New grant awarded for anemia treatment
Gene Transfer - Selective electroporation leaves adipocytes receptive to plasmid DNA
Genetic Recombination - New study links recombination rate with fertility
Genomics - Comparative study of Legionnaire's disease published
Genomics - Magazine publishes article on locating centromeres in plants
Genomics - Nucleic acid amplification company announces adoption of Ovation Biotin System
Genomics - Partnership formed to identify DNA variation in 20 strains of a plant
Genomics - Research company collaborates with scientists on BAC clone from tomato genome
Geobacillus Stearothermophilus V - Thermostable cysteine synthase from G. stearothermophilus V characterized
HIV/AIDS Research - Host cell gene expression varies during HIV-1 latency or reactivation
Hepatitis - Study reports results of PegIntron and Rebetol combination therapy for hepatitis
Infectious Disease - Company awarded SIBR grant for infectious disease detection
Macular Degeneration - Pharma company announces data for ocular disorders trial
Melanoma - B-RAF is therapeutic target in melanoma
Mergers & Acquisitions - Therapeutics company sells subsidiary to Neurogenesis Biotech
Mutagenesis - CPD-photolyase adenovirus-mediated gene transfer tracks photorepair in situ
Natriuretic Peptides - Current assays require refinement
Neurology - Anti-glucocorticoid gene delivery restructures neuronal stress response
Oncology - Anticancer agent may help induce cancer cell death
Oncology - FDA grants fast-track designation for metastatic melanoma treatment
Oncology - Restoration of metastasis suppressor genes could abate cancer dissemination
Oncolysis - Viral properties can be incorporated into adenovirus-based cancer therapies
Osteoporosis - Study shows once-monthly Boniva increases bone density and reduces breakdown
Osteoporosis - Women with osteoporosis treated with Actonel have good bone mineralization
Osteosarcoma - Trichostatin A offers novel therapeutic strategy for osteosarcoma
Parkinson Disease - Drug development company reports positive Parkinson disease study results
Peripheral Arterial Disease - Angiogenesis therapy successful for artery disease
Personnel - Biopharma company appoints vice president clinical research and development
Personnel - Biotechnology company elects members to board of directors
Personnel - Research institute appoints researcher specializing in nervous disorders
Product Licensing - Life sciences company, Rubicon Genomics sign genome amplification agreement
RNA Research - Intron arrays shed light on antisense intronic RNA in malignancies
SARS Coronavirus - Highly infectious SARS-CoV reveals cell tropism/receptor expression correlation
Sly Syndrome - Gene therapy overcomes blood-brain barrier to treat CNS manifestations
Stem Cell Research - Discoverer of DNA structure defends stem cell research opens exhibit
Stem Cell Research - Harvard researchers seek OK to produce cloned human embryos
Stem Cell Research - New report evaluates importance of cell therapy
Stem Cell Research - Science magazine hosts discussion of debate on embryonic stem cell research
Stem Cell Research - Stem cell research company provides update on programs
Stem Cells Research - Companies ink agreement for ACE system in adult-derived stem-cell research
Type 1 Diabetes - CTLA4 may be a susceptibility gene for type 1 diabetes
Vaccine Development - Memory T cells boost the DNA vaccine adjuvant interleukin-2/immunoglobulin
Vector Detection - Microarray screening can supply a vast selection of transgene candidates
Vector Development - Influenza A virus hemagglutinin constructs tend to lose fusion activity
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