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Genetic Recombination

New study links recombination rate with fertility

Published in Gene Therapy Weekly, November 4th, 2004

In a paper published in the October 3 online edition of Nature Genetics, a deCODE-led team of scientists presented the results of a large-scale population study linking recombination rate with maternal age and fertility.

The paper, entitled "Recombination rate and reproductive success in humans," establishes significant correlation between recombination - the shuffling of chromosomal material that takes place in the formation of eggs and sperm - and maternal age and fertility. Specifically, the average number of recombinations in eggs that go on to become successful live births tends to increase with the mother's age, and mothers with a higher recombination rate...

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