Pancreatic Cancer
Suppressed synthesis of HMGA1 protein treats pancreatic carcinomas in mice
Published in Gene Therapy Weekly, November 4th, 2004
According to a study from Italy, "pancreatic carcinoma is one of the most aggressive tumors, and, being refractory to conventional therapies, is an excellent target for new therapeutic approaches. Based on our previous finding of high HMGA1 expression in pancreatic cancer cells compared to normal pancreatic tissue, we evaluated whether suppression of HMGA1 protein expression could be a treatment option for patients affected by pancreatic cancer."
"Here we report that HMGA1 proteins are overexpressed in pancreatic carcinoma cell lines, and their downregulation through an...
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Source: Gene Therapy Weekly (2004-11-04)
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