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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . November 11th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Acute Liver Disease - Alpha-melanocyte-stimulating hormone gene transfer averts murine liver failure

Oncology - Inflammatory killing of normal cells might treat established tumors

Oncology - Novel adenoviral regulation drives gene expression in prostate cancer cells

Oncology - Synergy between DAC and cancer therapy fights lung cancer cell growth

Virology - Adenovirus vectors can not evade the memory immune response system

Alzheimer Disease - Biotech company announces results of Alzheimer study

Anthrax - Government to provide more funding for Anthim, an antianthrax drug

Antisense Technology - Select antisense molecules favor Duchenne muscular dystrophy exon 46 skipping

Autoimmunity - Retrogenic mice expand opportunities for exploring autoantigens

Breast Cancer - Ninety-seven grants awarded to breast cancer scientists and researchers

Breast Cancer - Promoter methylation of PTEN gene is common molecular change in breast cancer

Business & Finance - Biotechnology company announces commitment for $13 million equity financing

Cancer Therapy - Novel transplatinum drug ATZ interferes with topoisomerase I in cancer cells

Cardiology - Adenylyl cyclase type VI influences gene transcription in cardiac cells

Cardiology - Atrial and brain natriuretic peptide levels rise in the ischemic myocardium

Cardiology - Nuclear factor-kappa B decoy may treat cardiovascular and thrombotic diseases

Cardiology - Partnership restructures agreement to develop protein to aid in heart surgeries

Cardiomyopathy - Chemokine receptor DNA therapy prevents myocarditis-associated cardiac injury

Central Nervous System - TIMP-3 gene transfer affords partial protection to cortical neurons in rats

Cerebrovascular Disease - Global ischemia produces gene clusters that can index stress severity

Chemosensitization - A new multicomponent drug delivery system sensitizes lung cancer to therapy

Collaborations - Partnership to allow hospital and university system to share resources

Cushing Syndrome - GIPR regulatory genes are unlikely to underlie GIP-dependent Cushing syndrome

Diagnostics - Bioassays company announces U.S. Army contract, new kinase Activity Assays

Finance - Biotech listed as one of Maryland's fastest-growing technology companies

Finance - Enzyme-focused company announces $13.9 million private financing

Gene Delivery - Physical properties characterize the success of lipoplexes

Gene Expression - Transgene expression endures under the right conditions

Gene Mutation - Mutation hotspots in p53 gene depend on tumor type and cell growth conditions

Genomics - Companies team up to provide researchers human genomic DNA for gene regulation

Genomics - Genomics company and GlaxoSmithKline sign agreement for genome scanning project

Herpesvirus - DNA vaccine trial initiated for treatment of herpes simplex type 2

Immunology - Retroviral-mediated gene transfer corrects B-cell development in murine models

Leukemia - Hepatocyte growth factor sustains grafts after bone marrow transplantation

Licensing Agreement - Genzyme gets license for human genetic testing applications

Lung Cancer - Altered 14-3-3sigma/TEF1delta gene expression involved in lung carcinogenesis

Lysosomal Storage Disease - Genetically modified bone marrow treats mucopolysaccharidosis IIIB models

Multiple Sclerosis - MS patients on COPAXONE therapy for 10 years showed less disability progression

Multiple Sclerosis - Pharma company reports completion of animal model of multiple sclerosis

Muscle Wasting - Mechanism discovered for muscle wasting seen in diabetes, AIDS, other diseases

Myocardial Infarction - Combination gene therapy counteracts ventricular dilatation after heart attacks

Myocardial Infarction - Suppressed beta ARK1 helps murine models survive induced heart attacks

Neurology - Results of betaseron treatment in patients with multiple sclerosis announced

Neuroscience - In vivo plasmid DNA transfer identifies neurone-specific gene promoters

Neuroscience - Magnetic resonance imaging tracks neural progenitor cells in brain tumors

Oncogenesis - Partial pressure of oxygen fluctuations influence tumor dynamics

Oncology - Switch of a gene turns cancer cells healthy in mice, Stanford scientists find

Oncology - The methylation inhibitor zebularine selectively targets cancer cells

Ophthalmology - Cell death regulation company announces study published in journal

Personnel - Cellular therapy company names VP global marketing and communications

Receptor Studies - B-cell antigen receptor engagement improves adeno-associated virus transduction

Stem Cell Research - Researchers use modified blood stem cells to search for blood disease treatments

Stem Cell Research - Selective amplifier genes boost the utility of genetically modified cells

Stem Cells - New study shows most Americans support embryonic stem cell research

Suicide Gene Therapy - The SV40 enhancer and the HTERT gene promoter improve cancer gene therapy

Vector Development - Adenoviruses with alternate serotypes transduce glioma cell lines

Vector Development - Packaging cell lines offer a way to produce viral vectors in large quantities

Virology - Lipoplexes lose their stability during prolonged storage

Virology - Virally-driven small interfering RNAs silence genes in pancreatic cells

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