Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . November 25th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Therapy - Anticancer agents activate antiangiogenic gene therapy
Head and Neck Cancer - Suicide gene therapy and radiation kill nasopharyngeal carcinoma xenografts
Oncolysis - Antisense targeting of anti-apoptosis proteins radiosensitizes lung cancer
Urological Oncology - Downregulated Ets2 transcription factor halts prostate cancer cell growth
Vascular Gene Therapy - PMM2.1.2 nanoparticles augment peri-adventitial adenoviral gene delivery
Business & Finance - BioSciences company releases financial results
Business & Finance - Biopharmaceutical company announces third quarter 2004 results
Business & Finance - Company reports Q3 results, provides initial FDA guidance on DX-88 Program
Business & Finance - Pharmaceutical company reports financial results
Cancer Research - Drug used to stabilize vessels, block cancer cells from leaving bloodstream
Cancer Research - Pharma company provides Tarvacin IND update
Chemotherapy - APE/redox effector factor protein is a target for overcoming drug resistance
Collaborations - Drug discovery company, Novo Nordisk collaborate on TTP translational technology
Colon Cancer - Novel Bcl-2 family gene associated with progression of colon cancer
Dermatology - Apaf-1 may sensitize human cutaneous melanoma to cancer therapy
Diabetes - Partnership forged to uncover genetic basis for type 2 diabetes
Diabetes Complications - Intracorporal hSlo cDNA injections revive erectile capacity in diabetic rats
Diagnostics - Nanogen introduces diagnostic testing and diagnostic development platform
Diagnostics - Systems biology approach may bring new age of predictive, preventive medicine
Drug Development - Cancer-focused company reports atomic structure of c-KIT in complex with Gleevec
Drug Development - Light-directed gene delivery shows promise for therapeutic use
Endocrinology - Human islets contain tissue-restricted transcripts
Finance - Biopharmaceutical company reports third quarter increase of $1M
Finance - Hyaluronidase maker approved for listing on American Stock Exchange
Finance - Pharma company reports third quarter 2004 financial results
Gene Analysis - Microarray-based AMASE offers a novel way to scan for gene mutations
Gene Expression - Sterically stabilized immunolipoplex enhances systemic gene delivery
Gene Transfer - Complement improves the transduction of murine liver cells
Gene Transfer - Polypeptides with select binding affinities could direct genes to neurons
Genetic Testing - South Carolina screening newborns for more genetic disorders
Hematology - Mice expressing defective human factor IX aid hemophilia B research
Hepatocellular Carcinoma - Interleukin-12 gene transfer and electrosonporation targets liver cancer
Immunology - Fas ligand overexpression spawns inflammation in the central nervous system
Influenza Vaccine - Technology released for rapid production of influenza vaccines
Leukemia - Nippon Shinyaku Co., Ltd. receives approval to market TRISENOX in Japan
Leukemia - Orphan drug designation granted for the treatment of leukemia
Leukemia - Signaling mechanisms underlie human leukemia cell life/death switching
Lysosomal Storage Disease - Modified bone marrow cells improve cognition in mucopolysaccharidosis models
Mergers & Acquisitions - Biopharmaceutical company acquires minority interest in TKT Europe-5S AB
Molecular Biology - HNA gapmer oligonucleotides supply potent antisense activity
Molecular Imaging - PET reporters monitor activity following gene transfer
Multiple Sclerosis - Pharma company presents multiple sclerosis data at conference
Muscular Dystrophy - Dystrophin gene therapy overcomes immune system hurdles in murine models
Mutagenesis - Adenomatous polyposis coli gene isoforms curtail cancer cell growth
Myocardial Infarction - Heart cell therapy revitalizes the ailing heart
Myocardial Infarction - Interruption of the Fas/Fas ligand system may treat heart failure
Oncology - Bcl-xL gene overexpression boosts breast cancer lymph node metastasis
Oncology - Chromosome 9p21 shows a correlation with stage 4 neuroblastoma prognosis
Oncology - Genetic counselors and advocacy group develop genetic discrimination brochure
Ophthalmology - Smad7 gene transfer retains epithelial integrity in injured murine eyes
Osteogenesis Imperfecta - RNA interference targets COL1A1 expression in mesenchymal progenitor cells
Parkinson Disease - Pharma companies launch Parkinson disease study with Stalevo
Personnel - Biopharmaceutical company appoints executives
Personnel - Cockrell and Johnson appointed to senior positions at cell-therapy company
Prostate Cancer - CYP1B1 and PR polymorphisms may be associated with prostate cancer risk
Proteomics - A bidirectional on/off switch controls protein trafficking in the nucleus
Renal Cell Carcinoma - U.S. FDA grants orphan drug designation to BAY 43-9006
Restenosis - Calcitonin gene-related peptide gene transfer curtails neointimal hyperplasia
Schizophrenia - New data show metabolic and protein processing deficits may cause schizophrenia
Skin Cancer - New study examines skin protection in children
Small Cell Lung Cancer - Cancer therapeutics development company files IND for small cell lung cancer
Stem Cell Research - Companies ink agreement for new ES cell tissue-culture media
Tobacco Use - Research points to molecule that's key to nicotine addiction
Vaccine Development - License agreement reached for MedPulser DNA Delivery System in two applications
Vector Development - Fiber-mosaic adenovirus lends a new approach to adenoviral targeting
Vector Development - Preexisting diseases influence cytotoxic T-cell response to adenoviral vectors
Vector Development - The polymeric gene vector PLHP grants long-term gene delivery
Virology - Polyplexes containing chitosan oligomers improve non-viral gene delivery
Wound Care - Electroporation augments TGF-mediated healing in the wounds of diabetic mice
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