Oncology
Chromosome 9p21 shows a correlation with stage 4 neuroblastoma prognosis
Published in Gene Therapy Weekly, November 25th, 2004
"Chromosome 9p21 is frequently deleted in many cancers. Previous reports have indicated that 9p21 LOH is an uncommon finding in neuroblastoma (NB), a tumor of childhood. We have performed an extensive analysis of 9p21 and genes located in this region (cyclin-dependent kinase inhibitor 2A-CDKN2A/p16(INK4a), CDKN2A/p14(ARF), CDKN2B/p15(INK4b), MTAP, interferon alpha and beta cluster)," researchers in Spain report.
"LOH was detected in 16.4% of 177 NB. The shortest region of overlap (SRO) was identified between markers D9S1751 and D9S254, at 9p21-23, a region telomeric to the...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2004-11-25)
More Articles from Gene Therapy Weekly
- Cancer Therapy
Anticancer agents activate antiangiogenic gene therapy - Head and Neck Cancer
Suicide gene therapy and radiation kill nasopharyngeal carcinoma xenografts - Oncolysis
Antisense targeting of anti-apoptosis proteins radiosensitizes lung cancer - Urological Oncology
Downregulated Ets2 transcription factor halts prostate cancer cell growth - Vascular Gene Therapy
PMM2.1.2 nanoparticles augment peri-adventitial adenoviral gene delivery - Business & Finance
BioSciences company releases financial results - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
