Gastroenterology
Cytotoxic gene therapy is selective for human pancreatic cancer cells
Published in Gene Therapy Weekly, December 9th, 2004
According to a study from the United States, "the formation of a normal pancreas and the activation of insulin production are, in part, dependent on the expression and activation of the pancreatic duodenal homeobox gene 1 (PDX-1). The expression of PDX-1 also has been detected in various human pancreatic ductal adenocarcinoma (PDA) cell lines. This has made it possible to generate a cancer cell-specific gene expression system to treat human pancreatic cancer."
"In this study, we have developed a cell-specific cytotoxic model of PDA cells using the expression of herpes simplex...
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Source: Gene Therapy Weekly (2004-12-09)
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