Leukemic Stem Cells
Leukemic stem cells are a novel therapy target
Published in Gene Therapy Weekly, December 23rd, 2004
According to recent research from Austria, "Acute myeloid leukemia (AML) is a life-threatening hematopoietic disease that is characterized by clonal growth and the accumulation of myelopoietic progenitor cells.
"Although AML cells only have a limited potential to undergo differentiation and maturation, each AML clone is organized in a hierarchical manner similar to normal hematopoiesis."
"Recent data have shown that each AML clone consists of leukemic stem cells and their progeny, and that AML stem cells differ from more mature cells in several aspects, including survival and target...
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Source: Gene Therapy Weekly (2004-12-23)
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