Published in Gene Therapy Weekly, January 6th, 2005
"Following standard treatment, the prognosis remains poor in patients with high-grade glioma and new therapies are urgently required. Herpes simplex virus 1716 (HSV1716) is an ICP34.5 null mutant that is selectively replication competent and shown to be safe and to replicate following injection into high-grade glioma. We demonstrate that following surgical resection, HSV1716 is safe when injected into the brain adjacent to excised tumor," scientists in Scotland report.
"In all, 12 patients with recurrent or newly diagnosed high-grade glioma underwent maximal resection of the...
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