Gene Therapy Weekly

Implants - Blocking molecules protects health of implants

Inherited Diseases - Research hospital announces blindness treatment, new leadership

Liver Cancer - Sodium iodide symporter gene transfer augments iodine uptake in liver tumors

Liver Disease - Anti-monocyte chemoattractant protein-1 transfection prevents liver fibrosis

Male Sexual Function - Inducible nitric oxide synthase cDNA gene transfer ameliorates Peyronie disease

Mutagenesis - Overexpressed splicing factors restore normal protein function

Neurodegeneration - DNA peptide vaccination decreases amyloid plaques in Alzheimer disease models

Neurodegeneration - Recombinant DNA vaccine may jumpstart axonal regeneration

Neuroscience - Decorin transgene slows intracranial glioma progression in a rat model

Non-Hodgkin Lymphoma - Ganite activity in patients with advanced NHL presented at ASH meeting

Non-Hodgkin Lymphoma - Genasense shown to enhance the antilymphoma activity of Velcade and Rituxan

Oncogenesis - Silenced hdm2 prevents the growth of p53-dependent human breast cancer

Oncology - Aerosol delivery of tumor suppressor genes may treat lung cancer

Oncology - Liver X receptor agonists may have utility as antitumorigenic agents

Oncology - Small interfering RNA strikes down leukemia cell drug resistance

Oncolysis - HIF1-alpha antisense and chemotherapy boost cancer cell apoptosis

Oral Squamous Cell Carcinoma - P-cadherin expression may predict clinical outcome in OSCC

Organ Transplant - Chinese hospital claims success in digestive organs transplant

Orthopedics - Adenoviral-mediated transfer of the human BMP-6 gene generates bone repair

Orthopedics - Intra-arterial adenovirus-mediated gene delivery may revascularize bone

Pain Control - Bioengineered cells may treat opioid-sensitive chronic pain

Patents - Company seeks patent on large-scale manufacturing process for high-purity DNA

Personnel - Stuart M. Krassner, ScD, elected to pharmaceutical company board of directors

Prostate Cancer - Tissue-specific promoters work with small interfering RNA to downregulate genes

Protein Regulation - Exogenous designed regulatory protein modulates VEGF-A activity

Psoriasis - Texas researchers discover key protein in psoriasis

Radiotherapy - Nitric oxide and ionizing radiation activate p53 to generate apoptosis

Renal Cancer - CEACAM1 gene expression is reduced and reversible in renal cell carcinoma

Renal Toxicity - Midkine deletion protects the kidneys against cisplatin-induced injury

Rett Syndrome - Rett Syndrome organizations and National Institutes of Health partner

Stem Cell Research - AllCells' products to be distributed in Canada, the U.S. and France

Tissue Engineering - Runx2 brings mineralization to myoblast scaffolds designed to treat bone

Transcription - Hypermethylation represses inducible nitric oxide synthase gene function

Tumor Suppression - Fragile histidine triad protein has a dose-dependent effect on lung cancer

Vaccine Development - DNA vaccine breaks T cell tolerance to multidrug resistance-1 antigen in mice

Vaccine Development - Proteomics company enters agreement with Cytos Biotech for vaccine development

Vector Development - Adeno-associated virus gene vectors may treat hemophilia B

Virology - Delta-24 adenovirus infects and kills human medulloblastoma cells

Vitamins - New research on vitamin D offers significant therapeutic possibilities