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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . January 27th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Assisted Reproduction - Growth differentiation factor gene fragments treat porcine ovarian dysfunction

Cerebrovascular Disease - Homeobox D3 gene delivery initiates cerebral angiogenesis in mice

Gene Transfer - Jet injection and electroporation deliver plasmids to large muscles

Gene Transfer - Nucleotides targeting anti-apoptosis protein bind to erythroleukemia cells

Neurodegeneration - Beta-synuclein gene transfer protects mice from nervous system degeneration

Acute Myelogenous Leukemia - Clinical outcome not affected in pediatric AML patients with PTPN11 mutations

Assisted Reproduction - Biopharmaceutical company receives CE Mark for Cumulase

Atherosclerosis - Stent-based gene therapies offer a strategic way to treat arterial disease

Biological Therapy - DNA decontamination protocols will enhance the value of cell and gene therapies

Cancer Therapy - Protein arginine methyltransferase complexes regulate tumor suppressor genes

Candidemia - Antifungal medicine VFEND receives U.S. FDA approval for blood infection

Cerebrovascular Disease - Genes delivered following cerebral infarction improve neurological outcomes

Clinical Trials - Company provides update on cancer and HIV clinical-development programs

Clinical Trials - Results of autoimmune therapy in healthy volunteers study released

Colorectal Cancer - APAF-1 gene dysfunction from allelic imbalance increases with tumor progression

Congestive Heart Failure - Collaboration to develop AAV-based gene therapies for congestive heart failure

Cystic Fibrosis - Golf tournament raises money for cystic fibrosis foundation

DNA Research - Novel bleomycin conjugates cleave double-stranded DNA

Dermatology - Non-viral gene therapy may help patients with skin disorders

Dermatology - Semaphorin 3F prohibits melanoma metastasis

Drug Development - Companies enter partnership to commercialize functional human protein arrays

Drug Development - Ion exchange membranes capture vector-borne virus

Drug Development - Optimized freeze-drying keeps nonviral vectors stable during storage

Finance - DNA-focused company announces third quarter 2004 financial results

Finance - Drug discovery company announced private placement

Finance - Genetics-focused biopharmaceutical company reports Q3 2004 financial results

Finance - Protein-focused biopharmaceutical company reports Q3 2004 financial results

Gastric Cancer Diagnostics - LOH genotyping may be independent prognostic indicator in gastric carcinoma

Gastroenterology - Interferon-alpha and antisense K-ras RNA suppress pancreatic cancer cell growth

Gene Silencing - Retroviral driven transfer of short hairpin RNA analyzes gene function

Genetic Disorders - Dendritic cells made to express intereukin-12 prevent atopic disorders

Healthcare Access - New burn center celebrated at biosciences conference

Hematology - Novel ligand display technology transduces hematopoietic cells

Hematology - Prenatal gene therapy corrects hemophilia B in immunocompetent mice

Hepatitis C Therapy - Company reports results from phase Ia/Ib studies of Actilon for hepatitis C

Information Technology - Health information company launches enhanced health news channel

Lysosomal Storage Disease - Alpha-N-acetylglucosaminidase replacement treats Sanfilippo syndrome models

Malignant Mesothelioma - MM cells expressing Slug have increased resistance to chemotherapeutic agents

Multiple Sclerosis - Software selected to support multiple sclerosis research partnership

Neurodegeneration - New findings in neurodegeneration described

Neuroscience - Recent findings in neuroscience described

Neuroscience - Recent findings in neuroscience provide new insights

Neuroscience - The Wilms tumor gene is overexpressed in primary astrocytic tumors

Oncogenesis - Research in oncogenesis provides new insights

Patents - Biotech company acquires gene encoding patent from Akademikliniken AB of Sweden

Patents - Diagnostics products developer announces patent issuance

Patents - Patent granted for detecting environmentally toxic dioxin-like chemicals

Personnel - Biotechnology company appoints director of regulatory affairs

Personnel - California controller names Philip Pizzo, MD, to stem-cell oversight committee

Product Licensing - Biopharmaceutical company licenses human protein BPI to Zephyr Sciences, Inc.

Product Licensing - License agreement for glioblastoma multiforme treatment candidate signed

RNA Research - Fourier transform infrared spectroscopy discerns RNA bulge structures

RNA Research - RNA polymerase II-dependent promoter derivatives expand the potential of siRNA

Sarcoidosis - North Carolina researchers look for link to disease behind White's death

Stem Cell Research - Criticism of new $3 billion California stem cell agency mounts

Stem Cell Research - Non-muscle stem cells do not regenerate normal muscle tissue

Stem Cell Research - Nucleostemin plays important role in self-renewal of cancer cells

Stem Cell Research - StemCells Inc. seeks trial of stem cells in Batten disease

Stress Induction - Multiple stress signals induce p73 beta accumulation

Transfection - Researchers detail new studies and findings in the area of transfection

Vaccine Development - Dendritic cell expansion potentiates the immunogenicity of plasmid DNA vaccine

Virology - DNA aptamer prevents influenza infection

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