Oncogenesis
Research in oncogenesis provides new insights
Published in Gene Therapy Weekly, January 27th, 2005
Study 1: Silenced hdm2 prevents the growth of p53-dependent human breast cancer.
"RNA interference technology is a powerful tool for silencing endogenous or exogenous genes in mammalian cells. Here our results showed that hdm2-siRNA silenced its target mRNA specifically and effectively in human breast cancer cells, reduced tumor cell proliferation, and induced apoptotic cell death," scientists writing in the journal Cancer Gene Therapy report.
"Other molecular features modified by hdm2-siRNA included decreased...
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Source: Gene Therapy Weekly (2005-01-27)
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