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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . February 3rd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Bladder Cancer - Pretreatment compounds augment adenovirus-based transfection of the bladder

Breast Cancer - Mammaglobin-1 promoter enhances the transfection of mammary tumor cells

Drug Delivery - High-affinity antibody steers therapy to hepatocellular carcinoma

Drug Development - Hybrid viral vectors generate site-specific gene incorporation

Glioma - Antisense treatment combats orthotopic brain tumors in rodent models

Nasopharyngeal Cancer - Findings describe new data in nasopharyngeal cancer research

Virology - New findings in virology described

Angiology - Cells with hemangioblastic potential could treat several human diseases

Bacteriology - Antisense peptide nucleic acids end Staphylococcus aureus gene expression

Bioengineering - Engineered grafts could produce adenosine for therapeutic use

Bioengineering - Genetically modified progenitor cells augment therapeutic angiogenesis

Bioengineering - IND filed for human neural stem cell transplant treatment for Batten Disease

Bioengineering - Matrix-embedded marrow stromal cells provide long-term protein expression

Bioengineering - Scientists fail to establish consensus on defining a stem cell, continue debate

Biotechnology - Respiration in a bioengineered Saccharomyces cerevisiae revealed

Brain Cancer - Researchers' findings advance brain cancer research

Breast Cancer - Ectopic IRF-1 expression promotes tumor cell death

Breast Cancer - Gene vaccine protects mice against development of Her2/neu breast cancer

Business Update - BioSciences company announces research collaboration with Pfizer

Business Update - Genetics technology analysis company reports on MassARRAy system placements

Cancer Therapy - RNA interference curtails melanoma metastasis in xenografted mice

Cancer Therapy - Therapy directed against Bcl-2 helps rituximab limit lymphoma growth

Colon Cancer - PBR ligand-triggered signaling pathways lead to cell cycle arrest

DNA Research - DNA-binding agents make plasmid DNA transfection more efficient

Diet & Nutrition - Magazine details contents of health and life issue

Drug Delivery - PEG-conjugated PAMAM dendrimer is an efficient gene delivery carrier

Drug Development - Regimens combining antisense molecules with other drugs optimize outcomes

Duchenne Muscular Dystrophy - Costimulatory blockade boosts dystrophin gene expression after transfection

Endocrinology - Agouti-related protein gene transfer stimulates hormone-like effects in mice

Enzymology - Methylthioadenosine phosphorylase gene expression falters in liver disorders

Gastroenterology - Stabilized lipoplexes accelerate DNA release in liver cells

Gene Expression - Robust peptide nucleic acid distribution would improve their efficacy

Gene Transfer - Lithocholic acid backbones yield better oligodeoxyribonucleotide uptake

Gene Transfer - Phi C31 integrase and nucleofection create stable transgene expression

Genomics - Genomics company donates sorghum sequence to public domain

Gynecology - Findings in gynecology provide new insights

HIV/AIDS Epidemiology - Insight into the origins of the AIDS epidemic may offer new treatment approaches

Hematology - CRD-BP knockdown promotes leukemia cell proliferation

Hemophilia A - Megakaryocytes produce bioactive factor VIII after transfection

Immunology - Adenovirus-transduced dendritic cells stimulate CMV-specific T cells

Immunology - Reengineered stromal cells support the proliferation of naive T cells

Immunology - Researchers describe findings in immunology studies

Infections -  Staphylococcus aureus inhibition of keratinocyte migration revealed

Leukemia - Antisense molecules targeting Wilms tumor gene exon 5 may treat cancer

Mutagenesis - Aminoglycosides correct the phenotype of ataxiatelangiectsia cells

Oncology - Histone deacetylase inhibitor FR901228 defeats lung cancer cells

Oncology - Uncleavable pro-scatter factor obstructs tumor growth and dissemination

Personnel - David Ichikawa named senior VP, business development, by DNA-focused company

Personnel - Former governor James Greenwood assumes presidency of biotechnology association

Personnel - Michael Treble appointed CEO of pharmaceutical company's Ibis program

Vaccine Development - Immunization site stipulates the efficacy of tumor immunotherapy

Vascular Disease - Results of gene-transfer approach to vascular disease using stents published

Vector Development - Protein modifications amend adenovirus-induced toxicity

Vector Development - Star polymers ferry plasmids to cancer cells

Virology - Adeno-associated virus serotype 6 is an efficient gene vector

Virology - Findings describe new data in virology research

Virology - Lentivirus affords better cytokine coverage after dendritic cell transduction

Virology - Microsphere-liposome complexes shield gene vectors from neutralizing antibody

Virology - Reference assay allows comparisons of studies involving adenovirus type 5

Virology - Small chimeric intron sequences favor adenovirus-mediated gene transfer

Wilson Disease - ATP7B gene expression mitigates abnormal copper metabolism in rodent livers

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