Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . February 10th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Therapy - Oblimersen and vinorelbine diminish malignant lung tumors in murine models
Gastroenterology - Somatostatin receptor subtype 2 abates pancreatic cancer vessel formation
Occupational Health - Workers exposed to cystic fibrosis gene therapy rarely develop adverse effects
Oncology - Recent findings illuminate research in oncology
Oncology - Screened polymer libraries highlight optimal cancer gene therapy vectors
Oncology - Small interfering RNA augments hypoxia and radiation induced tumor cell death
Apoptosis - NDRG1 gene is necessary for p53-dependent apoptosis
Biomedical Engineering - A triplex-forming oligonucleotide conjugate directs site-specific binding
Breast Cancer - Gene vaccine protects mice against development of HER2/neu breast cancer
Breast Cancer - U.S. FDA approves albumin-bound nanoparticle paclitaxel for breast cancer
Business Update - Nucleic acids company launches new product line for protein sample preparation
Business Update - Pharma companies announce pharmacogenomics collaboration
Business Update - Pharmaceutical company outlines corporate restructure, research plans for 2005
Cancer Therapy - Oncolytic vesicular stomatitis virus localizes in breast cancer cells
Cancer Therapy - Researchers provide details of new studies and findings in the area of cancer therapy
Cancer Therapy - Telomere homolog oligonucleotides induce senescence in malignant fibroblasts
Cardiology - Bcl-2 upregulation modulates graft coronary artery disease in study models
Cardiology - Protein receptor reduces infarct size in ischemia/reperfused hearts
Diabetes Pathogenesis - Insulin signaling by RNAi-based gene silencing analyzed
Diabetes Therapy - Overexpressed heme oxygenase-1 lessens diabetes vascular complications
Diabetic Neuropathy - IND filed for DNA-binding protein therapeutic to treat diabetic neuropathy
Diagnostics - Ultrasound generates DNA fragments that are rapidly identified by biosensors
Drug Development - Availability of DNA-produced human growth hormone for AGHD in U.S. announced
Drug Development - Genomics company, Merck collaborate on development of novel therapeutic antibody
Enzymology - Data advance knowledge in enzymology research
Finance - Avastin maker reports strong 2004 results
Finance - Company gets $1M from CFFT to advance development of a nonviral gene therapy
Finance - Drug company reports strong fourth-quarter revenue growth
Gastroenterology - New findings in the area of gastroenterology described
Gastroenterology - Proangiogenic gene therapy accelerates duodenal ulcer healing
Gastroenterology - Restored receptor-type protein tyrosine phosphatase limits pancreatic cancer
Gene Delivery - Serum proteins alter the transfection quality of pGuaMA polyplexes
Gene Silencing - RNA interference stops proinflammatory signaling
Gene Silencing - Short synthetic DNA validates small interfering RNA
Gene Transfer - Synthetic cyclodextrin-based constructs carry genes to healing wounds
Genomics & Genetics - Promoters bound by ATF2 and c-Jun in genotoxic stress response identified
Hematology - Genetically modified progenitor cells correct thalassemia
Hematopoiesis - EDAG regulates proliferation and differentiation of hematopoietic cells
Hepatology - Gene transfection protects livers from ischemic injury
Huntington Disease - Companies establish collaboration to develop treatment for Huntington disease
Immunization - Fusogenic liposomal vector is a potent gene vaccine delivery vehicle
Immunology - Substitutions in mutant hepatitis B virus surface antigens are immunogenic
Infectious Disease Research - Company awarded $24 million to study genetics of infectious disease and vaccines
Influenza Vaccine - Data from Vaxin's first flu vaccine clinical trial reported
Lymphoma - Stem cell transplants viable option for patients suffering from lymphoma and HIV
Malignant Melanoma - Phase I clinical trial begins using MedPulser System
Mergers & Acquisitions - German pharmaceutical protein specialist ProThera acquired by chemical company
Myocardial Infarction - Insulin-like growth factor-1 fosters muscle cell survival after implantation
Myocardial Infarction - Tissue-specific gene transfer revives cardiac function in study models
Neural Stem Cell Research - Fetal neural progenitors can be the target for tumor transformation
Neuroscience - ALD-related gene targeting might benefit patients with X-adrenoleukodystrophy
Neuroscience - Cells bearing modified brain-derived neurotrophic factor yield neuroprotection
Neuroscience - Findings in neuroscience provide new insights
Oncogenesis - Fragile histidine triad gene inactivation supports bladder cancer formation
Oncology - Interleukin-12 gene therapy fights liver cancer in immunosuppressed mice
Oncology - Recent studies add new data to oncology research
Oncology - The ectodermal neural cortex 1 gene is upregulated in hairy cell leukemia
Organ Transplant - Daughter repays father with kidney
Orthopedics - Gene upregulation systems are expected to treat craniofacial bone defects
Patents - Patent issued for enhanced detection sensitivity in DNA materials analysis
Personnel - Biothrax maker names Dr. Steven Chatfield named chief scientific officer
Personnel - Genomics company adds new board member
Product Licensing - Geron agrees to distribution deal for telomerase-immortalized human cell lines
Product Licensing - Imaging systems company signs 5-year licensing agreement with Merck & Co., Inc.
Product Licensing - Protein research company announces licensing of flashBAC technology
Product Licensing - Therapeutics company licenses DISC-HSV and DISC-GM-CSF vector platforms
Professional Education - Library launches new open access journal for genetics and genomics community
Prostate Cancer - Protein kinase A regulatory subunits are targets for cancer gene therapy
Proteomics - Interleukin-6 conveys transcriptional regulation of the mu-opioid receptor
Pulmonary Medicine - Data advance knowledge in pulmonary medicine research
Pulmonary Medicine - Findings advance knowledge in pulmonary medicine research
Respiratory Medicine - Antisense molecules block asthmatic reactions in mice
Rheumatology - Baculovirus disseminates genes to rodent chondrocytes
Stem Cell Research - Nebraska bill aims to separate human cloning, stem cell issues
Transgenics - Intracytoplasmic sperm injection introduces DNA constructs to murine hosts
Vaccine Development - Combined vaccines synergize to resist cancer growth
Vector Development - Characterizations of charged interfaces provide insight into lipoplexes
Vector Development - DNA sequences maintain stability during plasmid processing
Vector Development - Retrotransposon-adenovirus hybrid vectors give long-term stable transduction
Virology - Genetic instability allows tumor cells to escape suicide gene therapy
Virology - Lentiviral vectors bestow advantages for targeted gene delivery
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