Gastroenterology
Somatostatin receptor subtype 2 abates pancreatic cancer vessel formation
Published in Gene Therapy Weekly, February 10th, 2005
According to a study from the Peoples Republic of China, "somatostatin receptor subtypes, especially subtype 2 (SSTR2), exert antitumor (cytostatic and/or cytotoxic) and antiangiogenic effects. Here we aimed to investigate the antiangiogenic effect of SSTR2 gene transfer into pancreatic cancer cell line PC-3, and the mechanisms involved in this effect."
"The full-length human SSTR2 complementary DNA was introduced into pancreatic cancer cell line PC-3 by lipofectamine-mediated transfection, and stable expression of SSTR2 was detected by immunohistochemistry and reverse...
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Source: Gene Therapy Weekly (2005-02-10)
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