Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . February 17th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Colon Cancer - Adjuvant interleukin-12 immunogene therapy manages metastatic lesions
Enzymology - Suicide gene therapy converts ethanol to a cancer cell toxin
Oncology - Antibody-mediated p53 transduction destroys cancer cells
Oncology - Antisense blockade of glucose transporter 5 cuts off breast cancer cell growth
Oncology - Reports add new data to oncology research
Vector Development - Replication-competent adenoviruses are safe gene and vaccine vectors
Allergy & Immunology - Down-regulated STAT6 curtails acute and chronic contact hypersensitivity
Atherosclerosis - E4F1 gene may be important in estrogen-related atheroprotection of human aorta
Biomedical Engineering - Programmable DNA microchips offer multiplex gene synthesis
Bone Cancer - Distinct gene signatures characterize the prognosis of Ewing sarcoma
Brain Cancer - Protein stops growth of brain tumor
Breast Cancer - FDA approves Abraxane, first in new class of protein-bound particle drug
Business Update - Molecular farming has potential for biopharmaceutical manufacturing, study says
Business Update - Research company forms subsidiary to develop cellular therapy technology
Cancer Therapy - Protein transduction domains enhance the oncolysis of tumor-specific viruses
Cancer Therapy - Research lifts major hurdle to gene therapy for cancer
Cardiology - Gene therapy thwarts atherosclerosis in apolipoprotein E-deficient mice
Clinical Trials - Companies announce plans to enter phase 3 trials on HSV-TK gene therapy project
Collaborations - Botulinum vaccine collaboration announced
Collaborations - Greenebaum Cancer Center enters oncology collaboration
Colon Cancer - Colorectal cancer gene patterns shift in response to neoadjuvant chemotherapy
Dermatology - STAT6 decoy oligodeoxynucleotide improves atopic dermatitis in mice
Diabetes Complications - KGF-1 gene transfer accelerates wound healing in diabetic mice
Drug Resistance - Antisense therapy reverses multidrug resistance in cancer cells
Drug Resistance - P-glycoprotein is a target for beating refractory autoimmune diseases
Endocrinology - The Id1 gene regulates the growth of thyroid cancer cells
Enterovirus 71 - Short hairpin RNAs developed to selectively inhibit enterovirus 71 replication
Finance - GVAX maker reports year-end net loss of $97.5 million
Finance - Human tissue products company reports preliminary fourth quarter revenues
Gene Transfer - Tethered mucins prevent adenoviral transfection of respiratory epithelium
Genetic Testing - Researchers show genetic tests may help avoid drug reactions
Genomics - Corn producers have access to 16 hybrids
Genomics - Scientists decipher two genomes of Cryptococcus neoformans
HIV Vaccine - Pharmaceutical company begins second phase I clinical trial of HIV vaccine
Head and Neck Cancer - Cks1 overexpression may foster oral squamous cell carcinoma formation
Head and Neck Cancer - Photochemical internalization and p53 gene transfer kindle cancer cell death
Head and Neck Cancer - Radiotherapy and gene therapy join to combat nasopharyngeal carcinoma
Hematopoiesis - PLZP disruption in Fanconi anemia and APL affect the biology of the HSC
Lipid Research - Experiments target membrane as site of action of polyunsaturated fatty acids
Liver Cancer - Caffeic acid and caffeic acid phenyl ester curb hepatoma growth and metastasis
Liver Cancer - Raf-1 causes radiation resistance in human hepatocellular carcinoma cells
Lysosomal Storage Disease - Transplanted neural progenitor cells decrease lysosomal storage pathology
Mutagenesis - Alpha(V) studied, functional effects of amino acid mutagenesis revealed
Myocardial Infarction - Restored S100A1 expression reverses cardiac dysfunction
Myocardial Infarction - SERCA1 overexpression triggers apoptosis in neonatal rat cardiomyocytes
Neuropathy - Gene transfer supplants liver transplant as amyloidotic polyneuropathy therapy
Neuroscience - Suppressed nuclear factor-kappa B p65 protects retinal neurons from injury
Oncology - Herpes simplex virus thymidine kinase transduction expands colon cancer growth
Ophthalmology - Small interfering RNA ameliorates neovascularization-related eye disorders
Parkinson Disease - Adenoviral-induced production of transcription factor Gli1 is neuroprotective
Patents - Genetics company issued two U.S. patents for cancer treatment
Prostate Cancer - First phase of prostate cancer detection system development complete
Proteomics - Chinese hamster ovary cells spawn recombinant protein after transfection
Pulmonary Medicine - Studies add new findings to pulmonary medicine body of knowledge
Restenosis - Dominant negative protein receptor mitigates arterial hyperplasia
Stem Cell Research - A mutant fusion gene protects hematopoietic stem cells from chemotherapy
Transplant Medicine - Girl with blood disease undergoes bone marrow transplant
Vector Development - Adeno-associated virus transduction requires intracellular viral processing
Vector Development - Reports advance knowledge in vector development research
Vector Development - Studies advance knowledge in vector development research
Virology - Lentiviruses carry out efficient cancer cell transfection
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