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Colon Cancer

Adjuvant interleukin-12 immunogene therapy manages metastatic lesions

Published in Gene Therapy Weekly, February 17th, 2005

Adjuvant interleukin-12 immunogene therapy manages metastatic lesions.

"In humans, no efficient treatment exists not only against multifocal liver metastases (LM) but also against recurrent microscopic liver metastases within the liver remnant following curative liver resection. Furthermore, in non-multifocal LM, partial liver resection could be performed, but in more than 50% of the patients, tumor recurrence within liver remnant is observed, partly due to the growth of dormant cancer cells in the setting of postoperative host immune dysfunction," investigators in France report.

"We investigated the therapeutic potential of interleukin-12 (IL-12)...

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