Genomics

Scientists decipher two genomes of Cryptococcus neoformans

Published in Gene Therapy Weekly, February 17th, 2005

In a project that already has benefited an important field of biomedical research, scientists have deciphered the genomes of two closely related strains of Cryptococcus neoformans, a fungus whose importance as a human pathogen has risen in parallel with the HIV/AIDS worldwide epidemic and the increased use of immunosuppressive therapies.

The study, posted online in Science Express, revealed differences in the virulence strategies used by C. neoformans compared to other pathogenic fungi. Researchers also examined the genetic determinants of its pathogenicity by comparing the genomes of two closely related strains of significantly different...

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Source: Gene Therapy Weekly (2005-02-17)

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