Non-viral gene knockdown may treat neurological and psychiatric disorders

According to published research from Switzerland, "gene expression analysis implicates an increasing number of novel genes in the brain as potential targets for the treatment of neurological and psychiatric disorders."

"Frequently, these genes are ubiquitously expressed in the brain and, thus, may contribute to a pathophysiological state through actions in several brain nuclei. Current strategies employing genetically modified animals for in vivo validation of such targets are time-consuming and often limited by developmental adaptations," noted D.R. Thakker and colleagues,...

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