Susan Hasty, Publisher
Table of Contents . . . March 17th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Oncology - Antisense CK2 causes prostate cancer cells to self-destruct
Oncology - CpG oligonucleotide and rituximab combine to attack non-Hodgkin lymphoma
Oncology - Gene silencing curbs the growth of breast cancer cells
Vector Development - Viral vector follows anti-mesothelin antibody to ovarian cancer cells
Virology - Semliki Forest virus vector battles fast growing murine tumors
Allergy and Immunology - Local gene therapy can help dendritic cells fight tumor growth
Angiology - Hypoxia-specific vector driven gene therapy diminishes tumor angiogenesis
Ascorbic Acid - Vitamin C conjugation is a pathway for elimination of electrophilic LPO products
Awards - Award sponsorship for outstanding investigator in single molecule biology set
Bifidobacterium Bifidum - Monomeric aspartate racemase Bifidobacterium bifidum molecularly analyzed
Biomedical Engineering - Biotechnology company reports progress in avian transgenics biomanufacturing
Biomedical Engineering - Life-sciences high-tech company introduces gene knockout system
Biotechnology - Lymphoid human cell line DG75 efficient for somatic gene targeting
Bioterrorism - Company initiates animal studies on compound to treat exposure to terror weapons
Bladder Cancer - HER3 and HER4 expression associated with better survival in bladder cancer
Brain Cancer - Michigan researcher vies for funding to research brain cancer
Breast & Prostate Cancer - ICAM gene region is breast and prostate cancer susceptibility locus
Breast Cancer - Estrogen receptor mutations identified in cancer & psychiatric disease
Breast Cancer - Gene study sheds light on a type of breast cancer
Breast Cancer - Polymorphisms in MMP genes can influence breast cancer phenotype
Breast Cancer Risk Factors - Integrin beta(3) Leu33Pro polymorphism may increase breast cancer risk by age 45
Business & Finance - Albuferon maker reports increased net loss in 2004, provides clinical update
Business & Finance - DNA-focused biopharmaceutical company announces fourth quarter, year end results
Business Update - ChromaVision Medical Systems to change name
Business Update - New agreements to provide kinase drug screening service for 4 companies signed
Cancer Stem Cells - Cancer stem cells isolated from adult glioblastoma multiforme
Cancer Therapy - Caveolin gene delivery diminishes tumor angiogenesis by targeting nitric oxide
Cancer Therapy - Strategies to disrupt anti-apoptosis protein must overcome major hurdles
Collaborations - First groundbreaking held in U of California San Diego Science Research Park
Collaborations - Hospital and university partner to develop health service and education programs
Colon Cancer - Age-related ERRP loss in aging colon is potential risk factor for colon cancer
Dermatology - Stat3 can be targeted for the treatment of psoriasis
Diabetes Pathogenesis - Findings in diabetes pathogenesis provide new insights
Diabetes Therapy - Overexpressed IRS2 protects human beta-cells from hyperglycemia-induced death
Diagnostics - Assays used to identify potential treatments for drug-resistant strain of HIV
Diagnostics - Joey Diagnostic device that tests cord blood of newborn ready for use
Diagnotics - PCR-based method accurately detects thalassemia mutations in cord blood
Drug Delivery - Automatic insulin delivery device, insulin cartridge launched in India
Drug Development - p73 induction after DNA damage is regulated by Chk1 and Chk2
Embryonic Stem Cell Research - Human feeder cells support maintenance of embryonic stem cells in culture
Fetal Stem Cell Research - Fetal bone cells potential use for tissue engineering
Gastroenterology - Researchers describe findings in gastroenterology studies
Gene Research - CuraGen exercises option to expand antibody-drug conjugate collaboration
Gene Research - Separating chromosomes may improve genetic test results, study shows
Genetics - Ohio research center to tailor healthcare based on genes
Genetics and Genomics - Research company performs computational analysis of the human genome
Genomics - DNA microarrays play key role in Human Genome Project
Glioma - Drug in trials to treat glioma obtains orphan drug designation in Japan
Growth Hormone Deficiency - Generic-drug company and Savient launch pediatric growth hormone treatment
Growth Hormone Deficiency - Pharmaceutical companies offer product for pediatric growth hormone deficiency
Gynecology - Adeno-associated virus vector transmits therapeutic ligand to ovarian cancer
Hematology - Gene therapy offers hope for correcting hemophilia
Hepatitis C Therapy - Drug development companies to codevelop recombinant human alfa interferon
Leukemia - AML1-ETO C-terminal NcoR/SMRT-interacting region deletion induces leukemia
Leukemia - Gamida-Cell and Teva to develop and commercialize StemEx for leukemia
Leukemia - Generic drug company, Gamida-Cell to develop StemEx for treatment of leukemia
Lung Cancer Pathogenesis - Immortalized bronchial epithelial cells useful to study lung cancer pathogenesis
Mergers & Acquisitions - Agriculture company to acquire Emergent Genetics, Inc.
Myogenesis - Short interfering RNA elucidates the role of S1P in myogenic differentiation
Neuroscience - Light chain gene delivery yields focused neural inhibition
Neuroscience - Microscopy-based techniques monitor lentivirus-mediated neuron modifications
Oncology - CagA structure variability may explain H. pylori-related diseases
Oncology - Gene sets identify hepatitis B virus-related liver cancer
Oncology - Researchers provide details of new studies and findings in the area of oncology
Osteoarthritis - Enzyme restoration using gene delivery promotes cartilage repair
Ovarian Cancer - Collaboration to further research into ovarian cancer biomarkers
Ovarian Cancer - Researchers further evaluate OvaRex Mab for ovarian cancer
Pancreatic Cancer - IFN-gamma polymorphisms correlate with duration of survival in pancreatic cancer
Personnel - Pharmaceutical company adds to scientific resource board
Personnel - Protein therapeutics-focused company expands management team
Product Licensing - Agreement will bring fluorous separation technology to oligonucleotide synthesis
Product Licensing - Pharmaceutical company acquires access to TrueClone Collection
Prostate Cancer - HOXB13 suppresses growth of prostate cancer cells
Proteomics - Altered cellular signals augment RNA interference in neuroblastoma cells
Renal Disease - Ex vivo decorin gene transfer halts renal extracellular matrix deposition
Retinopathy - Intraocular PEDF gene therapy prevents light-induced cell death
Rheumatology - Agents targeting signal transduction pathways ease rheumatoid arthritis
Stem Cell Research - Ink4a/ARF links senescence and aging
Stem Cell Research - Letter of Intent filed with U.S. NIH for stem cell research center grant
Stem Cell Research - Suits filed to invalidate California's $3 billion stem cell institute
Vaccine Development - DNA vaccine targeting survivin eradicates lung tumor growth and metastasis
Vector Development - Intrahepatic hydrodynamics-based gene delivery generates human protein
Vector Development - Naked DNA plasmid GTU-multiHIV disseminates and persists in lymph nodes
Vector Development - Polymeric complexes exhibit high transfection efficiency
Vector Development - VP22 is ineffective for conveying intercellular gene trafficking
Virology - Interleukin-12 restores immune responses in chronic hepatitis C patients
Virology - RNA interference uses several pathways to block viral infection
Virology - Researchers describe findings in virology studies
Xeroderma Pigmentosum - In world without sun, life revolves around ill daughter
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