Gene Therapy Weekly

Allergy and Immunology - Small molecule inhibitors suppress nanoparticle-mediated inflammatory response

Gastroenterology - TRAIL gene transfer keeps pancreatic tumors from growing in murine livers

Obstetrics - Adenoviral vectors deliver genes to fetal murine muscle in utero

Oncology - CXCR4 knockdown slows breast tumor growth and invasion

Oncology - Gene silencing sensitizes prostate cancer to cancer therapy

Acute Intracerebral Hemorrhage - Journal publishes results of acute intracerebral hemorrhage study

Addiction Medicine - Cocaine hydrolase gene delivery blunts the heart's response to cocaine

Adverse Drug Reaction - Macrophages produce enzyme after chitosan-DNA nanoparticle delivery

Allergy and Immunology - Constructs with membrane bound or secreted GITR-L bypass immune suppression

Allergy and Immunology - Costimulatory cytokines rescue CD8+ T cell response to peptide immunization

Biomedical Engineering - Coded nanoparticles present a way to monitor transfection after gene delivery

Biomedical Engineering - Effect of lypholization on some therapeutic recombinant proteins studied

Biomedical Engineering - Life sciences company launches functional p53 protein microarray

Biomedical Engineering - Sonic hedgehog gene enhanced tissue engineering stimulates bone formation

Blood Safety - 54-year-old woman dies after receiving wrong blood

Brain Cancer - New findings in the area of brain cancer detailed

Business & Finance - Diagnostics/lab service company reports dip in revenue, changes name

Business & Finance - Pharma company announces financial results

Business Update - Biopharma company signs agreement with Celliance BioServices, Inc.

Business Update - Gene therapy company reports progress of avian transgenic biomanufacturing

Business Update - Sentigen Holding Corp. Announces the Sale of Its Specialty Media Division

Cancer Therapy - Antagonists to melanoma-inhibiting activity foil immunosuppression

Cancer Therapy - Findings advance knowledge in cancer therapy research

Cancer Therapy - Infusions of gene therapy-sponge mixtures may beat human liver cancer

Cardiology - Enzyme inhibitors attenuate ventricular dysfunction after pressure overload

Collaborations - Pharmaceutical companies enter biogeneric partnership

Colorectal Cancer - Research company awarded grant to study DNA mutations in colorectal cancer

Coronary Heart Disease - A three allelic SNP is strongly associated with plasma CRP concentration

DNA Vaccine - Bacterial DNA-specific modified base triggers cytokine production in mice

Disease Associations - CFTR folding analyzed, contributions of side chain and backbone revealed

Drug Delivery - Agreement signed for needle-free delivery system for human growth hormone

Drug Development - Antisense blockade of ICAM-1 does not harm fetal development in study models

Drug Development - Immunoliposome-encapsulated plasmid DNA characterized

Drug Development - Research finds pharmacogenomics alters balance of power in drug development

Endocrinology - Endoplasmic reticulum stress contributes to insulin resistance and diabetes

Endocrinology - Excess resistin production alters lipid levels in mice

Endocrinology - Prohormone convertase studied, role in glucagon formation revealed

Endometriosis - Enhanced gene expression may confer resistance to cytokine-induced apoptosis

Finance - Company focused on metabolic disorders reports Q4 and 2004 financial results

Finance - Company focused on protein deficiency treatments reports strong 2004 financials

Finance - DX-88 and DX-890 maker reports increased net loss

Finance - Developer, manufacturer of human cell lines reports 2004 results

Finance - HIF-focused company completes equity financing

Finance - Medical company allocates money to venture capital fund, changes personnel

Finance - RNA-focused biotech company reports Q4 and full-year financial results

Finance - Supplier to drug discovery industry reports Q4 full year 2004 financial report

Gastroenterology - Recombinant viral vectors generate unrestricted liver cell transduction

Gene Research - Genome sequence of tularemia bacterium analyzed

Gene Research - Nonenzymatic nucleic acid labeling kits for DNA microarray applications launched

Gene Silencing - RNA interference selectively silences angiotensin receptor subtype 1a