Oncology
Orally administered bacteria transport anticancer genes in mice
Published in Gene Therapy Weekly, March 24th, 2005
"To overcome difficulties that hampered widespread application of a specific delivery system in cancer gene therapy and to inhibit the growth of solid liver cancer, we utilized a strain of Bifidobacterium longum as a delivery system to transport an endostatin gene that can inhibit growth of tumor," investigators in the Peoples Republic of China report.
"The B. longum strain with the endostatin gene (B.longum-En) was taken orally by tumor-bearing nude mice through drencher preparation. The results showed that B. longum-En could strongly inhibit the growth of...
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Source: Gene Therapy Weekly (2005-03-24)
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