Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . April 7th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Colon Cancer - Gene replacement therapy suppresses colorectal tumors in animal models
Neuroscience - Marrow stromal cells aid axonal regeneration after spinal cord injury
Oncology - Progression-elevated gene-3 promoter selects cancer cells for gene delivery
Renal Cancer - Antisense oligonucleotide to Ki-67 limits tumor growth but not vessel density
Age-Related Macular Degeneration - Gene believed responsible for age-related macular degeneration discovered
Allergy and Immunology - RNA transcripts are targets for asthma therapy
Angina - Positive gene therapy trial results for angina published
Atherosclerosis - Mouse gene turned on by fatty food linked to human heart-disease gene
Bioartificial Liver - Collagen/chitosan/heparin improves hepatic tissue engineering biocompatibility
Biomedical Engineering - Chitosan improves cationic emulsion-mediated gene transfer
Virology - Recent findings illuminate research in virology
Biomedical Engineering - Company dedicates expanded kinase screening facility in Dundee, Scotland
Bioterrorism - U.S. NIAID $15 million contract awarded to develop three monoclonal antibodies
Brain Cancer - Therapy against protein kinase C cedes little relief to glioma patients
Business & Finance - Biopharma company announces financial results
Cancer Drugs - Mithramycin inactivated ADH enzyme by inducing structural change
Cancer Drugs - RLIP76 transported vinorelbine and mediated drug resistance in NSCLC
Cancer Genetics - BRCA1 and BRCA2 breast tumor development pathways may differ
Cancer Genetics - Database for gene expression profiling compiled in the CGED
Cancer Genetics - Inhibiting angiotensin II may prevent or treat breast cancer
Cancer Immunotherapy - CpG oligodeoxynucleotides activate tumor-specific immune responses
Cancer Therapy - Adenovirus-delivered anti-Tie-2 intrabody shuts down tumor angiogenesis
Chemoreceptors - E. coli Tar chemoreceptor analyzed, nature of signaling state defined
Clinical Trials - Enrollment in phase 1 clinical trial of atherosclerosis treatment begun
Clinical Trials - Enrollment of phase 2 clinical trial of antibody for treatment of HIV complete
DNA Research - TAT/DNA polyplexes analyzed, influence of TAT-peptide polymerization detailed
Drug Development - Encapsulated cells release soluble factors after brain implantation
Finance - Newborn stem-cell bank reports record growth in revenue
Finance - Stem cell-focused biotech company announces Q4, year end 2004 financial results
Gene Research - Genetic therapy reverses nervous system damage in animal model
Gene Research - Genetics-focused company announces distribution alliance with Transgenomic, Inc.
Gene Research - Many variables limit autogene-based cytoplasmic expression systems
Gene Silencing - Small interfering RNA downregulates protein expression in rodent grafts
Gynecology - Sentinel cells expand upon CpG oligodeoxynucleotide transfer in the vagina
Human Papillomavirus - HPV-13 polymorphisms determined for HIV+ and women at risk for HIV infection
Infectious Disease - Corporation reports initial success of specific antibody development
Matrix Metalloproteinase - CD44 shedding studied, role of hemopexin-like domain shown
Mergers & Acquisitions - Biotechnology company completes purchase of Protexia operations and assets
Multiple Myeloma - External analyses of multiple myeloma trial announced
Neurodegeneration - Apolipoprotein E gene transfer alters Abeta in Alzheimer disease models
Neurology - Nogo receptor studied, effects of genetic deletion clarified
Neuroscience - Glial cell line-derived neurotrophic factor ameliorates neurodegeneration
Oncology - Down-regulation of the Ku system promoted progression of urinary bladder cancer
Oncology - Gene networks reverse breast cancer tumorigenesis after chromosome 8 delivery
Oncology - Reports add new data to oncology research
Oncology - The carboxyl-terminal repressor domain of MBP-1 stops prostate cancer growth
Personnel - Defense contractor hires consultant to develop stem cell research center grant
Personnel - Margaret A. Liu, MD, appointed to board of DNA-focused biosciences company
Personnel - William Claypool, MD, appointed to board of morphogenics-focused biotech company
Pituitary Glands - EGF stimulated transcription of hPRL in human breast cancer SK-BR-3 cells
Product Licensing - Chemicon licenses Quantum Dot antibody reagent line
Prostate Cancer - Silencing of polo-like kinase 1 induced apoptosis of prostate cancer cells
Protein Interactions - Protein-protein c-Myc interactions studied, specific inhibition described
Proteomics - Transient transfection technology scales up protein production
Stem Cell Research - Bcl-2 reduced/Fas activated by SCF/KIT inhibition signaling in melanocyte SCs
Stem Cell Research - Prominin-1/CD133 is expressed certain types of kidney cancer
Stem Cell Research - United Nations votes to ban human cloning
Vector Development - Inorganic phosphate nanoparticles support efficient pDNA transfection
Vector Development - Non-viral gene vectors composed of copolymers stabilize gene transfer
Vector Development - Small peptides provide controlled release of DNA from fibrin matrices
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