Skin Cancer
Alterations of mtDNA in malignant melanoma not induced by UV radiation
Published in Gene Therapy Weekly, April 14th, 2005
According to recent research published in the journal Melanoma Research, "UV radiation is thought to be a major contributor to the development of sporadic malignant melanoma of the skin. It may induce alterations in genomic or mitochondrial DNA (mtDNA), especially C to T or CC to TT changes. Mutations or other alterations in mtDNA have been reported in a variety of human cancers and may be due to different mechanisms."
"In this study, we have attempted to elucidate whether aberrations in the mtDNA of melanoma are due to...
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Source: Gene Therapy Weekly (2005-04-14)
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