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Stomach Cancer

Carcinogenesis potential predicted by analyzing RUNX3 expression topographically

Published in Gene Therapy Weekly, April 14th, 2005

Scientists analyzed RUNX3 expression topographically to determine the potential for gastric carcinogenesis in the remnant stomach and adjacent mucosa.

"Our previous studies suggest that a lack of RUNX3 function is causally related to the genesis and progression of human gastric cancer," scientists reported in the British Journal of Cancer.

"This study was conducted to determine whether alteration of RUNX3 gene expression could be detected in the normal-looking gastric remnant mucosa, and to ascertain any difference in the potential of gastric carcinogenesis between the anastomotic site and other areas in the remnant stomach after distal...

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