Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . April 21st, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Enzymology - Inducible caspase-9 disrupts neovascular growth after adenoviral delivery
Gastroenterology - Intraperitoneal antisense K-ras RNA suppresses pancreatic cancer dissemination
Gene Transfer - Contact lens-type electrodes enhance gene delivery in retinal ganglion cells
Gene Transfer - Suicide gene therapy kills glioma cells using a bystander effect
Neuroscience - Virus-mediated endostatin gene transfer may cure malignant brain tumors
Addiction Medicine - Tumor necrosis factor antisense therapy fights alcoholic liver disease
Allergy and Immunology - Chimeric constructs generate recombinant IgE antibody upon transfection
Allergy and Immunology - Vaccine containing CpG oligodeoxynucleotides heighten immune activation
Antimicrobials - Antimicrobial activity of melittin examined, effect of deletion revealed
Apoptosis - Metal-induced fibroblast apoptosis examined, nature of augmentation clarified
Asthma - Asthma deemed the ugly duckling of lung disease proteomics
Oncology - Recent findings illuminate research in oncology
Bioinformatics - Bioinformatics is a multifaceted discipline combining many scientific fields
Biomedical Engineering - Plasmid expression vectors regenerate frog skeletal muscle
Cancer Gene Therapy - FGF20 targeted by beta-catenin and implicated in cancer development
Cancer Genes - Promoter of novel cancer-related gene 1A6/DRIM was identified and characterized
Cardiology - Cardiac K+ channel analyzed, Ca2+ influence clarified
Drug Development - The new aptamer ARC245 binds to and inhibits VEGF activity
Oncology - Research in oncology provides new insights
Gastroenterology - Reports describe recent advances in gastroenterology research
Gene Silencing - Small interfering RNA discourages coxsackievirus B3 replication
Glioblastoma Multiforme - Recombinant targeted toxin TP-38 can produce sustained response
Head & Neck Cancer - Retinol-binding proteins silenced in nasopharyngeal carcinoma
Head and Neck Cancer - Researchers' data advance head and neck cancer research
Hematology - B-cell lymphomas respond differentially to CpG oligodeoxynucleotides
Oncology - Studies advance knowledge in oncology research
Hematology - Cryopreserved umbilical cord blood yields mesenchymal stem cells
Hepatitis B Therapy - RNA interference counteracts hepatitis B virus replication
Interleukin Receptors - Transcriptional regulator examined, influence on kinase 2 promoter clarified
Leukemia Tumorigenesis - Evi3 expression in tumors altered level of EBF target genes in leukemia
Liver Tumorigenesis - Liver tumorigenesis modulated in connexin32-deficient mice
Melanoma - Protective effect of quercetin and luteolin in melanoma HMB-2 cells reviewed
Mergers & Acquisitions - Biologics manufacturing business sold for $80 million to Ferring subsidiaries
Mouse Skin Carcinogenesis - Antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis
Muscular Dystrophy - Studies describe new findings in muscular dystrophy research
Oncology - Findings describe new data in oncology research
Oncology - Retroviral insertional mutagenesis divulges the complexities of carcinogenesis
Oncology - Survivin may be suited for tumor-specific gene promotion in melanoma
Oncolysis - Microarray explores adenovirus-mediated E2F-1-induced apoptosis
Ovarian Cancer - Cell surface carbohydrates involved in biological properties of cancer cells
Patents - European, Canadian allowances granted for anticancer drug in phase 2 trials
Pediatric Lymphoma - Genes cooperate to provoke immune system cancer B-cell lymphomas, study shows
Peptide Receptors - Gastrin-releasing peptide receptor studied, critical amino acids identified
Peripheral Nerve Sheath Tumors - Expression patterns of cell cycle components in MPNSTs detailed
Personnel - Genetic personalization-focused company hires Stephen Benoit, Tod Kimbell
Personnel - Madhusudan V. Peshwa, PhD, named VP, R&D by clinical stage therapeutics company
Pompe Disease - Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
Product Licensing - Option agreement signed to license selective engraftment of certain stem cells
Renal Disease - Ultrasound-microbubble-mediated gene transfer treats rodent kidney fibrosis
Retinopathy - Oligonucleotide therapies show promise for treating retinal disease
Stomach & Colon Cancer - Foxl1 implicated in carcinogenesis of stomach and colon cancers
Vector Development - Co-emulsifiers improve the efficacy of lipid emulsion-based transfection
Vector Development - Genetic approaches improve the acquisition of pCOR plasmids
Vector Development - Guanidinium headgroups extend the viability of non-viral gene vectors
Vector Development - Nucleofection sends complementary DNA into rodent neurons
Vector Development - Pyridinium cationic lipids are well-suited for non-viral gene delivery
Virology - Adenoviral signatures have implications for human drug development
Virology - Caffeine keeps retroviruses from transducing nondividing cells
Virology - Cellular gene regulation by viral vectors raises quality control concerns
Virology - Double expression vectors offer simultaneous gene knockdown
Wound Repair - Ex vivo gene therapy heals fractures in osteoporotic animals
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