Gene Therapy Weekly

Diabetic Neuropathy - Hepatocyte growth factor gene transfer improves neuropathy in diabetic rats

Gene Transfer - Combined gene therapy regimens demolish cancer proliferation

Lung Cancer - Overexpressed soluble TRAIL initiates the destruction of lung adenocarcinoma

Oncology - Chimeric enhancer controls adenovirus-based prostate cancer gene therapy

Oncology - Silenced insulin-like growth factor binding protein-5 restricts neuroblastoma

Angiology - Recent studies add new data to angiology research

Apoptosis - Intracellular overproduction of apolipoprotein L6 induced apoptosis

Apoptosis - Resveratrol regulated PKC alpha and delta to inhibit growth and induce apoptosis

Autoimmune Disease - Reprogrammed dendritic cells prevent experimental autoimmune encephalomyelitis

Biomedical Engineering - MR images trace the path of genetically engineered natural killer cells

Biomedical Engineering - Preadipocyte differentiation enhances insulin production

Oncology - Findings advance knowledge in oncology research

Breast Cancer - MTHFR 677T variant/low folate associated with increased risk of breast cancer

Breast Cancer - PKC delta and MAPK mediate G(1) arrest induced by PMA in SKBR-3 breast cancer

Breast Cancer Therapy - Single-agent trastuzumab show promise for breast cancer

Business & Finance - Genetics company reports Q4 net loss of $3,708,000

Cancer Cachexia - Effect of cancer cachexia on the activity of tripeptidyl-peptidase II measured

Cancer Cell Apoptosis - Tumor cells sensitized to apoptosis by selective inhibition of specific Akt/PKB

Oncology - Findings in oncology provide new insights

Cancer Diagnosis - Clonal abnormalities in Philadelphia-positive ALL and CML analyzed

Cancer Drugs - Extravascular transport of drugs in tumor tissue examined

Cancer Immunotherapy - Fusion protein fights cervical cancer in murine models

Cancer Prodrugs - Formaldehyde and butyric acid exhibited anticancer activity

Cancer Therapy - Antitumor activity of measles virus studied

Cancer Therapy - Findings describe new data in cancer therapy research

Oncology - New findings in oncology described

Cancer Therapy - Human MUC1 oncoprotein regulated p53-responsive gene transcription

Cancer Therapy - Novel mechanism of checkpoint abrogation conferred by Chk1 downregulation

Cancer Therapy - Silatecan DB-67 showed promise in treating cancer

Cancer Therapy - Transcription factor 3 contributed to curcumin's proapoptotic effect

Cardiology - Sarcalumenin deficiency studied, impaired Ca²⁺ muscle stores revealed

Colon Cancer - Cytokine gene transfer halts the growth of colon cancer cells

Oncology - Reports add new data to oncology research

Colorectal Cancer - Abnormal p53 increases risk of death in colorectal cancer

Colorectal Cancer - Beta-catenin and APOE SNPs associated with positive family history of cancer

Colorectal Cancer - Mutations in TGFBR2 and BAX in neoplastic progression and patient outcome

Colorectal Cancer - Promoter methylation downregulates CDX2 expression in colorectal carcinomas

DNA Binding - Combinatorial identification of the covalent DNA-binding polyamide tallimustine

DNA Research - Nucleotide sequence variation found often in mitochondrial DNA of tumor cells

Oncology - Research add new data to oncology body of knowledge

DNA Tumor Viruses - Hope placed in DNA tumor viruses to help understand cancer cell programming

Dermatology - Antisense oligodeoxynucleotide G3139 activates melanoma cell apoptosis

Diagnostics - DHPLC superior to SSCP in screening p53 mutations in esophageal cancer tissues

Disease Associations - G_q/11 family g proteins studied, link to hypoplasia and dwarfism revealed

Drug Delivery - Cell-specific systems improve drug and gene delivery

Drug Delivery - Polyethylene glycol shifts the dynamics of liposomal clearance

Virology - Studies add new findings to virology body of knowledge

Epstein-Barr Virus - PSK and Trx80 inhibit EBV-induced B-cell proliferation

Esophageal Cancer - Defective mismatch-repair linked to Barrett esophagus-associated adenocarcinoma

Follicular Thyroid Cancer - Expression profiling revealed transcription signature in thyroid carcinomas

Gastric Cancer - Lysophospholipids transactivate HER2/neu (ErbB-2) in gastric cancer cells

Gender Medicine - Sex-specific gene profiles help personalize hepatitis C-related cancer therapy

Gene Delivery - Findings describe new data in gene delivery research

Gene Research - Bacterial artificial chromosome transgenesis verifies RNA interference

Gene Research - Slowed replication fork progression enhances oligonucleotide-based gene repair

Genetic Engineering - Human genes corrected