Cardiac Research
Overexpressed oxygen-regulated protein minimizes cardiac injury
Published in Gene Therapy Weekly, May 19th, 2005
"Early contractile dysfunction and the later death of cardiomyocytes are two major problems that can follow myocardial infarction or major cardiovascular surgery that demands ischemic arrest of the heart. Here, we found that 24 h of hypoxia and 1 h of reoxygenation induced the expression of the chaperone ORP150 in cultured rat cardiomyocytes," scientists writing in the Journal of Molecular and Cellular Cardiology report.
"Inhibition of its induction using an adenovirus to express antisense ORP150 significantly enhanced the hypoxia-reoxygenation-induced cardiomyocyte death; cell...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2005-05-19)
More Articles from Gene Therapy Weekly
- Bone Cancer
Liposome complexes containing endostatin abate osteosarcoma metastasis - Gastroenterology
Carboxylesterase-2 gene therapy sensitizes colon cancer cells to chemotherapy - Oncology
4T1 tumor cells determine the true fate of cancer gene therapy - Stroke
Midkine gene transfer protects brain cells against focal ischemia - Virology
Inactivated adenoviruses in microbead conjugates transfect targeted cells - Acute Lymphoblastic Leukemia
RAS mutation associated with hyperdiploidy/parental characteristics in ALL - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
