Endocrinology

Researchers' work adds to endocrinology body of knowledge

Published in Gene Therapy Weekly, May 19th, 2005

Endocrinology data are the focus of recent research from Argentina, France and the South Africa.

Study 1: Limited diffusion impedes the transfection of pituitary tumors.

"Suicide gene therapy has met limited success for the treatment of rat pituitary tumors. In order to determine the cause of primary pituitary tumor resistance to suicide gene therapy, we studied the transgene expression of an adenoviral (Ad.RSV.betagal.nls) and a herpes simplex virus-derived (tsK/beta-gal) vector, both harboring the beta-galactosidase reporter gene in rat prolactinomas," researchers in Argentina report.

"Rats carrying experimental prolactinomas...

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Source: Gene Therapy Weekly (2005-05-19)

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