Published in Gene Therapy Weekly, May 19th, 2005
"We developed a new low invasive cell manipulation and gene or molecule transfer system in a single living cell by using an atomic force microscope (AFM) and ultra thin needle, a nanoneedle," investigators in Japan report.
"DNA was immobilized on the surface of the nanoneedle by covalent bonding and avidin-biotin affinity binding. Immobilization of DNA on the nanoneedle was confirmed by measuring the unbinding force between avidin and biotin," wrote S.W. Han and colleagues, National Institute of Advanced Industrial Science and Technology (AIST), Research Institute for Cell...
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