Heat Shock Protein
Heat shock protein 70 examined, role in clonogenicity of leukemic cells revealed
Published in Gene Therapy Weekly, May 26th, 2005
"Pretreatment of human leukemia THP-1 cells with Hsp70 protected them from the cell-lethal effects of the topoisomerase II inhibitor, lucanthone and from ionizing radiation," wrote R. Bases and colleagues, Montefiore Medical Center.
"Cell viability was scored in clonogenic assays of single cells grown in liquid medium containing 0.5% methyl cellulose. Colonies were observed and rapidly scored after staining with the tetrazolium salt, 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl...
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Source: Gene Therapy Weekly (2005-05-26)
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