Muscular Dystrophy
Findings advance knowledge in muscular dystrophy research
Published in Gene Therapy Weekly, May 26th, 2005
Study 1: Dual hybrid vectors restore dystrophin synthesis in murine muscles.
According to a study from Netherlands, "Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene, making it a potential target for gene therapy. There is, however, a scarcity of vectors that can accommodate the 14-kb DMD cDNA and permanently genetically correct muscle tissue in vivo or proliferating myogenic progenitors in vitro for use in autologous transplantation."
"Here, a dual high-capacity adenovirus-adeno-associated virus (hcAd/AAV)...
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Source: Gene Therapy Weekly (2005-05-26)
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