Published in Gene Therapy Weekly, June 2nd, 2005
According to researchers in Japan, "we examined the antitumor effect and safety of the adenovirus-mediated expression of antisense K-ras RNA in two peritoneal dissemination models of pancreatic cancer. First, we found that the infection of an adenovirus vector expressing antisense human K-ras RNA (AxCA-AS) induced significant apoptosis in vitro in human pancreatic cancer cells with K-ras mutation."
"Second, the intraperitoneal (i.p.) injection of AxCA-AS effectively suppressed the...
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