Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . June 9th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Gastroenterology - Antisense trefoil factor family-3 sensitizes gastric cancer to adryamicin
Hematology - Bcl-2 antisense G3139 uptake is achievable in acute myeloid leukemia cells
Oncology - Clusterin inhibition enhances prostate cancer's response to primary therapy
Urology - Clusterin antisense inactivates radioresistance in bladder cancer cells
Vector Development - Replication-competent retroviral vectors host long-term transgene expression
Acute Myeloid Leukemia - Dominant negative effects of AML1/ETO may be important for AML pathogenesis
Angiology - Researchers provide details of new studies and findings in the area of angiology
Apoptosis - Boswellic acid acetate induces apoptosis via caspase-mediated pathways
Bladder Cancer - Preclinical research programs at universities added to bladder cancer studies
Brain Cancer - Cell and virus-specific elements control photochemical-induced transfection
Breast Cancer - Endoxifen showed tamoxifen-like, anti-estrogenic effects in breast cancer cells
Neuroscience - Recent findings in neuroscience described
Breast Cancer - NCOA3 polymorphisms associated with protective effect against breast cancer
Business & Finance - Biotechnology company completes $3.37 million financing
Business & Finance - Molecular engineering-focused corporation reports first quarter 2005 results
Cancer Genetics - New configurations of action in cancer genetics practices discussed
Cancer Therapy - Immune-response strategy to be tested for use against cancer
Cancer Therapy - Pituitary tumor-transforming gene depletion eradicates tumor growth
Oncology - Recent findings in oncology described
Cervical Cancer - HLA-B8 overrepresented in cervical cancer compared to MHC-1 in healthy controls
DNA - DNA repair gene TP53/POLI/REV1/LIG4 SNPs associated with lung cancer risk
Disease Associations - Tau pathology in astrocytes studied, role of transgenic mouse model reported
Drug Delivery - A new method for creating stabilized plasmid lipid particles offers scalability
Drug Delivery - Recent findings illuminate research in drug delivery
Drug Delivery - Ultrasound-induced cavitation sends drugs and genes into cancer cells
Oncology - Reports advance knowledge in oncology research
Drug Development - Company applies to FDA for orphan drug status of lysosomal acid lipase product
Drug Development - Molecular engineering biotech company, Bayer CropScience sign research agreement
Drug Resistance - Antisense oligodeoxynucleotide-doxorubicin conjugate garners chemosensitivity
Enzymology - Extracellular matrix metalloproteinase inducer uses VEGF to fuel angiogenesis
Enzymology - uPAR antisense oligonucleotide prevents prostate cancer bone metastasis in mice
Epidermolysis Bullosa - Dundee scientists on road to cure for "butterfly children" condition
Oncology - Research add new data to oncology body of knowledge
Epstein-Barr Virus - EBV BARF1-encoded protein expressed from tetracycline-regulatable ADV system
Finance - Cell therapeutics-focused corporation announces third quarter 2005 results
Finance - Genomics-focused biotechnology company reports first quarter 2005 results
Finance - Life science, diagnostic products company reports strong Q1 2005 results
Gastroenterology - Downregulated XIAP expression causes gastric cancer cells to self-destruct
Gastroenterology - Tpr-Met RNA interference is a potent gastric cancer fighter
Gene Expression - LKLF-regulated genes identified in quiescent CD4+ T lymphocytes
Gene Research - Ligand-regulated Flpe mediates DNA recombination and responds to tamoxifen
Gene Research - Nucleotide identity and base pair position rule aspects of RNA interference
Gene Transfer - Co-delivered mutant IkappaBalpha enhances suicide gene therapy
Gene Transfer - Recent findings illuminate research in gene transfer
Genetics & Genomics - Biotech company introduces novel gene-targeting enzymes
Hematology - Membrane immunoglobulin engagement boosts promoter activity in lymphoma cells
Hepatitis B Therapy - Interferon gamma gene delivery controls hepatitis B virus replication
Herpesvirus - Varicella-zoster virus examined, roles of an open reading frame revealed
Information Technology - Research institute selects informatics platform for transitional medicine
Legionellosis - Pathogen effector protein screening used, Legionella factors identified
Leishmaniasis - Leishmania major chromosome 1 analyzed, gene disruption ploidy changes described
Lung Cancer - Inhibitor kappaB alpha gene transfer blocks lung tumor growth and angiogenesis
Mammary Cancer - Soluble tumor-associated antigens inhibit chemically-induced mammary cancer
Melanoma - Biallelic deletions in INK4 in melanoma associated with decreased survival
Morphogenesis - Candida albicans morphogenesis studied, involvement of kinase clarified
Neuroblastoma - N-Myc linked to death receptor machinery in neuroblastoma cells
Neurology - Alpha-synuclein accumulation examined, lysosomal pathology clarified
Neurology - CREB-binding protein studied, hippocampal effects of truncation clarified
Neuroscience - Findings describe new data in neuroscience research
Neuroscience - Hypoxia triggers apoptosis in brain tumors made to express BAX
Oncology - Corticosteroid adversely affects HSV-tk/ganciclovir suicide gene therapy
Oncology - Data advance knowledge in oncology research
Oncology - Dominant-negative growth factor receptor fights gastric cancer progression
Oncology - Fibroblast growth factor gene disruption inhibits synovial sarcoma growth
Oncology - Small interfering RNA targeting VEGF staunches Ewing sarcoma in murine models
Ophthalmology - Short interfering RNAs deploy to combat choroidal neovascularization
Parkinson Disease - Research in Parkinson disease provides new insights
Patents - Life science, diagnostic products company files patent infringement suit
Patents - New patent issued to University of Pennsylvania for hyperlipidemia treatment
Physiology - Protein overexpression studied, femoral effects revealed by infrared imaging
Product Licensing - Diagnostics company expands agreement with Applera Corporation
Product Licensing - Pharmaceutical company exercises option for additional antigen
Prostate Cancer - Phase 1 data on OGX-011 trial presented at conference
Prostate Cancer - Tomoregulin is a valid target for radioimmunotherapy in prostate cancer
Skin Cancer - Matrilysin-2 upregulated in keratinocytes during wound repair/early skin cancer
Squamous Cell Carcinoma - E-cadherin is a strong prognostic factor in squamous cell carcinoma
Stem Cell Gene Therapy - Breast cancer resistance protein is marker in SC gene therapy applications
Stem Cell Research - Down-regulation of SSX impairs cell migration and MMP2 expression
Stem Cell Research - Peroxisome proliferator-activated receptors are targets for drug development
Transplant Medicine - Dual gene transfer staunches acute lung graft rejection in rats
Vaccine Vector - Adenovirus cross-reactivity in delayed-type hypersensitivity examined
Vaccine Vector - Cross-linked small polyethylenimines deliver DNA to mammalian cells
Vector Development - Complex mosaicism boosts the infectivity of adenovirus type 5-based vectors
Virology - Endocytosis rallies adenoviral uptake in photochemically treated cells
Virology - Researchers report details of new studies and findings in the area of virology
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