Published in Gene Therapy Weekly, June 16th, 2005
Study 1: Pseudotype baculoviruses support ligand-directed gene targeting.
"The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) can infect a variety of mammalian cells, as well as insect cells, facilitating its use as a viral vector for gene delivery into mammalian cells. Glycoprotein gp64, a major component of the budded AcMNPV envelope, is involved in viral entry into cells by receptor-mediated endocytosis and subsequent membrane fusion," researchers in Japan report.
"We examined the potential production of pseudotype...
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