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Virology

Research add new data to virology body of knowledge

Published in Gene Therapy Weekly, June 16th, 2005

New findings from Japan, Finland and Singapore describe advances in virology.

Study 1: Pseudotype baculoviruses support ligand-directed gene targeting.

"The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) can infect a variety of mammalian cells, as well as insect cells, facilitating its use as a viral vector for gene delivery into mammalian cells. Glycoprotein gp64, a major component of the budded AcMNPV envelope, is involved in viral entry into cells by receptor-mediated endocytosis and subsequent membrane fusion," researchers in Japan report.

"We examined the potential production of pseudotype...

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