Lung Cancer
Endostatin gene therapy and radiotherapy abate lung tumor growth
Published in Gene Therapy Weekly, June 16th, 2005
According to a study from the United States, "targeting cells that support tumor growth by administering potent angiogenesis inhibitors is currently an area of intense interest. In the present study, a unique plasmid vector for the mouse endostatin gene, pXLG-mEndo, was constructed and evaluated with and without radiation using the Lewis lung carcinoma (LLC) cell line."
"The physical properties of the expressed endostatin protein were validated by polymerase chain reaction (PCR), gel electrophoresis, and Western blot. Enzyme-linked immunosorbent and immunocytochemical analyses for the...
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Source: Gene Therapy Weekly (2005-06-16)
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